Iwasaki Masaki
Department of Neurosurgery, National Center Hospital, National Center of Neurology and Psychiatry.
Brain Nerve. 2023 Apr;75(4):341-345. doi: 10.11477/mf.1416202336.
Drug-resistant epilepsy is defined when epileptic seizures are not controlled for over a year despite adequate use of two or more anti-epileptic drugs. Patients with drug-resistant epilepsy should be referred to a specialized epilepsy center without delay. The epilepsy centers provide long-term video-EEG monitoring and epilepsy surgery as essential medical functions. The diagnosis and treatment of epilepsy are reviewed through an interdisciplinary care team approach. A surgical indication is discussed and determined after a comprehensive evaluation of patients with drug-resistant epilepsy. The number of epilepsy surgeries performed per population in Japan is approximately 40% of that in the United States. However, the number of epilepsy centers and the number of video-EEGs performed remain low. It is expected to facilitate patients' access to specialized care in Japan.
耐药性癫痫的定义为,尽管充分使用了两种或更多种抗癫痫药物,但癫痫发作仍持续一年以上未得到控制。耐药性癫痫患者应立即转诊至专业癫痫中心。癫痫中心提供长期视频脑电图监测和癫痫手术等重要医疗服务。通过多学科护理团队的方式对癫痫的诊断和治疗进行评估。对耐药性癫痫患者进行全面评估后,讨论并确定手术指征。日本每人口进行的癫痫手术数量约为美国的40%。然而,癫痫中心的数量以及视频脑电图检查的数量仍然较少。预计这将有助于日本患者获得专科护理。