Mazzaferri E L
Postgrad Med. 1986 May 15;79(7):64-72. doi: 10.1080/00325481.1986.11699409.
Hypothyroidism ranges in severity from subtle alterations of thyroid function to myxedema coma. Its manifestations in other organ systems or as behavioral changes effectively draw attention away from the thyroid. Normal findings on physical examination and an elevated serum thyroid-stimulating hormone (TSH) level are characteristic of mild hypothyroidism. Therapy with thyroid hormone may be indicated. Myxedema coma is an endocrine emergency, usually precipitated by some stressful event, eg, infection, medication, exposure to cold, severe hemorrhage. Because time is usually insufficient for full-scale endocrine evaluation, diagnosis must be based on history, physical examination, and exclusion of other causes of coma.
甲状腺功能减退症的严重程度不一，从甲状腺功能的细微改变到黏液性水肿昏迷。它在其他器官系统的表现或行为改变有效地转移了人们对甲状腺的注意力。体格检查正常但血清促甲状腺激素（TSH）水平升高是轻度甲状腺功能减退症的特征。可能需要进行甲状腺激素治疗。黏液性水肿昏迷是一种内分泌急症，通常由某些应激事件诱发，如感染、药物、受寒、严重出血。由于通常没有足够时间进行全面的内分泌评估，诊断必须基于病史、体格检查以及排除其他导致昏迷的原因。
