Faculty of Science, Department of Health Sciences, Section Youth and Lifestyle, Vrije Universiteit Amsterdam, De Boelelaan 1085, Amsterdam, 1081 HV, The Netherlands.
BMC Pediatr. 2023 Apr 11;23(1):167. doi: 10.1186/s12887-023-03973-8.
It is unknown whether weight class is associated with impairment of health-related quality of life (HRQOL) for children in the Netherlands. The aim of this study was to explore generic and weight-specific HRQOL in a clinical cohort of children with overweight, obesity or severe obesity aged 5-19 years in the Netherlands.
803 children from three clinical cohorts participated: mean age 11.5 (SD 2.9) years, 61.1% girls. The influence of weight class was explored in a subgroup of 425 children (25.2% with overweight, 32.5% obesity and 42.3% severe obesity), of whom the exact International Obesity Task Force (IOTF) BMI class was known. Generic HRQOL was measured by the PedsQL child report. Weight-specific HRQOL was measured by the IWQOL-Kids child or parent report. Average total, subscale and item scores were reported and the influence of the IOTF BMI class analyzed by multiple linear regression, corrected for age and sex.
Children with severe obesity had lower generic and weight-specific HRQOL scores than those with obesity or overweight. IOTF BMI class was negatively associated with item scores from all subscales, especially physical, social and emotional functioning. Children with overweight reported similar HRQOL total, subscale and item scores to children with obesity.
In the Netherlands, children treated for overweight, obesity or severe obesity experience problems on the majority of items within all subscales of generic and weight-specific HRQOL. Children with severe obesity especially report significantly more challenges due to their weight than children with obesity or overweight.
目前尚不清楚体重类别是否与荷兰儿童健康相关生活质量（HRQOL）受损有关。本研究旨在探讨荷兰超重、肥胖或重度肥胖儿童临床队列的通用和特定于体重的 HRQOL。
来自三个临床队列的 803 名儿童参与了该研究：平均年龄为 11.5（SD 2.9）岁，61.1%为女孩。在 425 名儿童的亚组中（25.2%超重，32.5%肥胖，42.3%重度肥胖），探索了体重类别的影响，其中确切的国际肥胖工作组（IOTF）BMI 类别是已知的。通用 HRQOL 通过 PedsQL 儿童报告进行测量。特定于体重的 HRQOL 通过 IWQOL-Kids 儿童或家长报告进行测量。报告了平均总分、子量表和项目得分，并通过多元线性回归分析了 IOTF BMI 类别的影响，同时校正了年龄和性别。
重度肥胖儿童的通用和特定于体重的 HRQOL 得分低于肥胖或超重儿童。IOTF BMI 类别与所有子量表的项目得分呈负相关，特别是身体、社会和情感功能。超重儿童的 HRQOL 总分、子量表和项目得分与肥胖儿童相似。
在荷兰，接受超重、肥胖或重度肥胖治疗的儿童在通用和特定于体重的 HRQOL 的所有子量表中的大多数项目上都存在问题。特别是重度肥胖的儿童比肥胖或超重的儿童报告更多的体重相关问题。
