Technol Health Care. 2023;31(S1):533-540. doi: 10.3233/THC-236047.
The incidence rate for migraine is 12% worldwide, and recurrence is common, which seriously affects the physical and mental health of patients.
To observe the clinical effect of Shallow Puncture and More Twirling method of acupuncture in treating migraine and its impact on serum 5-HT and β-EP.
A total of 76 patients with migraine were randomized into a control group and acupuncture group with 38 cases in each. In the control group, patients were orally administered flunarizine hydrochloride before sleep, 2 capsules once daily for 4 weeks. In the acupuncture group, Shallow Puncture and More Twirling method was adopted for the acupoints of Sizhukong (SJ 23), Toulinqi (GB 15) Shuaigu (GB 8), Xuanlu (GB 5), Fengchi (GB 20), Waiguan (SJ 5), Zulinqi (GB 41). Patients were given acupuncture 3 times per week for 4 weeks. Then, the total VAS (Visual Analogue Scale) scores, composite score of migraine, serum level of 5-HT and β-EP, and the clinical efficacy differences were observed before and after treatment and the side-effects were recorded among the two groups.
The total VAS scores and composite score of migraine were significantly reduced among both groups after the treatment (P< 0.05), and the serum level of 5-HT and β-EP was significantly improved (P< 0.05). Compared with control group, the acupuncture group reported lower results in VAS score and migraine composite score (P< 0.05), and higher results in serum 5-HT and β-EP level (P< 0.05). The acupuncture group with shallow puncture and more twirling method showed a total effective rate of 86.5%, which is higher than the control group (78.4%). The difference is statistically significant (P< 0.05).
Shallow Puncture and More Twirling method was superior to flunarizine hydrochloride in the treatment of clinical symptoms of migraine. Acupuncture also increases the serum level of 5-HT and β-EP in migraine.
偏头痛的发病率在全球范围内为 12%，且易复发，严重影响患者身心健康。
观察浅刺多捻针法治疗偏头痛的临床疗效及其对血清 5-羟色胺（5-HT）和β-内啡肽（β-EP）的影响。
将 76 例偏头痛患者随机分为对照组和针刺组，每组 38 例。对照组患者每晚睡前口服盐酸氟桂利嗪胶囊，每次 2 粒，连续服用 4 周。针刺组采用浅刺多捻针法针刺四神聪（SJ23）、头临泣（GB15）、率谷（GB8）、悬颅（GB5）、风池（GB20）、外关（SJ5）、足临泣（GB41），每周 3 次，连续治疗 4 周。观察两组患者治疗前后的视觉模拟评分（VAS）总评分、偏头痛综合评分、血清 5-HT 和β-EP 水平的变化及临床疗效差异，并记录不良反应。
两组患者治疗后 VAS 总评分和偏头痛综合评分均较治疗前降低（P<0.05），血清 5-HT 和β-EP 水平均较治疗前升高（P<0.05）；针刺组 VAS 评分和偏头痛综合评分低于对照组（P<0.05），血清 5-HT 和β-EP 水平高于对照组（P<0.05）；针刺组总有效率为 86.5%，高于对照组的 78.4%，差异有统计学意义（P<0.05）。
浅刺多捻针法治疗偏头痛的临床症状优于盐酸氟桂利嗪胶囊，且能提高偏头痛患者血清 5-HT 和β-EP 水平。
