减重手术后的胃癌。它们有关联吗？（一项系统评价）。
Gastric cancer after Bariatric Bypass Surgery. Do they relate? (A Systematic Review).
机构信息
Department of Medicine, Division of Gastroenterology and Hepatology, Saint Peter's University Hospital/Rutgers-RWJ Medical School, 254 Easton Avenue, New Brunswick, NJ, 08901, USA.
Departmengt of Surgery, Yale University School of Medicine, New Haven, CT, 06510, USA.
出版信息
Obes Surg. 2023 Jun;33(6):1876-1888. doi: 10.1007/s11695-023-06567-6. Epub 2023 Apr 11.
Bariatric bypass surgery has been an effective treatment for morbid obesity. However, there is an increasing number of reported cases of gastric cancer after bypass surgery. Our systematic review showed an increasing trend of gastric cancer cases after bariatric bypass surgery in the last decade, mostly located in the excluded stomach (77%) and diagnosed in an advanced stage. In addition to known risk factors such as tobacco smoking (17%), H. pylori infection (6%), and family history of gastric cancer (3%), bile reflux, a recently proposed cancer-promoting factor, was also estimated in 18% of the cases. Our data suggest that gastric cancer risk assessment should be considered before gastric bypass surgery, and further investigations are needed to determine the value of post-operative gastric cancer surveillance.
减重手术已成为治疗病态肥胖症的有效方法。然而，手术后胃癌的报告病例数量正在不断增加。我们的系统综述显示，在过去十年中，减重手术后胃癌的病例呈上升趋势，大多数发生在被排除的胃部（77%）且处于晚期诊断。除了已知的风险因素，如吸烟（17%）、幽门螺杆菌感染（6%）和胃癌家族史（3%），最近提出的促癌因素胆汁反流也在 18%的病例中被估算到。我们的数据表明，在进行胃旁路手术前应考虑胃癌风险评估，需要进一步研究以确定术后胃癌监测的价值。
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