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商业制造的髋关节假体周围感染治疗用间隔物。

Commercially manufactured spacers for the treatment of periprosthetic joint infection of the hip.

机构信息

Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinik Bonn, Venusberg-Campus 1, 53105, Bonn, Germany.

出版信息

Oper Orthop Traumatol. 2023 Jun;35(3-4):179-187. doi: 10.1007/s00064-023-00802-0. Epub 2023 Apr 11.

DOI:10.1007/s00064-023-00802-0
PMID:37041387
Abstract

BACKGROUND

Periprosthetic joint infection remains a common and serious complication after hip arthroplasty. To improve function and patient comfort after joint removal in two-stage revision, commercially manufactured spacers for the hip joint allow retention of the anatomical joint geometry thereby limiting soft tissue contraction and allow mobilization.

INDICATIONS

Periprosthetic joint infection of the hip, septic arthritis with severe destruction of the hip cartilage and/or bone requiring arthroplasty.

CONTRAINDICATIONS

Allergies to polymethylmethacrylate (PMMA) or antibiotics, severe hip dysplasia with insufficient cranial support, incompliant patient, large osseous defect of the acetabulum, insufficient metaphyseal/diaphyseal support of the femoral bone, resistance of the microbiological pathogen to spacer-inert antibiotic medication, inability to perform primary wound closure requiring temporary open-wound therapy.

SURGICAL TECHNIQUE

Preoperative templating on radiograph; removal of joint prosthesis and thorough debridement with removal of all foreign material; trial spacer selection and insertion and trial reduction of the joint, fixing the spacer with PMMA to the proximal femur, final reduction, radiograph and stability test.

RESULTS

Data were analyzed from patients treated between 2016 and 2021. In all, 20 patients were treated with preformed spacers and 16 with custom-made spacers. Pathogens were detected in 23 of the 36 cases (64%). Polymicrobial infections were present in 8 of 36 cases (22%). In patients who received preformed spacers, there were 6 cases of spacer-related complications (30%). Of the 36 patients (83%), 30 were reimplanted with a new implant; 3 patients died due to septic or other complications before reimplantation (8%). Average follow-up was 20.2 months after reimplantation. There were no major differences between the two groups of spacers. Patient comfort was not measured.

摘要

背景

髋关节置换术后,假体周围关节感染仍然是一种常见且严重的并发症。为了在两阶段翻修中关节切除后改善功能和患者舒适度,商业制造的髋关节间隔器允许保留解剖关节几何形状,从而限制软组织收缩并允许活动。

适应证

髋关节假体周围感染、伴有髋关节软骨和/或骨严重破坏的化脓性关节炎,需要进行关节置换。

禁忌证

对聚甲基丙烯酸甲酯(PMMA)或抗生素过敏、严重髋关节发育不良伴头侧支撑不足、不配合的患者、髋臼大骨缺损、股骨骨干骺端支持不足、微生物病原体对间隔器惰性抗生素药物耐药、无法进行一期伤口闭合需要临时开放伤口治疗。

手术技术

术前在 X 线片上进行模板设计;切除关节假体并彻底清创,去除所有异物;试装间隔器选择和插入,并试复位关节,用 PMMA 将间隔器固定到股骨近端,最终复位,拍摄 X 线片并进行稳定性测试。

结果

分析了 2016 年至 2021 年期间治疗的患者数据。共有 20 例患者接受预制间隔器治疗,16 例患者接受定制间隔器治疗。在 36 例中,有 23 例(64%)检测到病原体。36 例中有 8 例(22%)为混合感染。接受预制间隔器治疗的患者中有 6 例发生与间隔器相关的并发症(30%)。在 36 例患者中(83%),有 30 例用新植入物重新植入;在重新植入前,有 3 例患者因脓毒症或其他并发症死亡(8%)。重新植入后的平均随访时间为 20.2 个月。两种间隔器之间没有显著差异。未测量患者舒适度。

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本文引用的文献

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Projected Economic Burden of Periprosthetic Joint Infection of the Hip and Knee in the United States.美国人工髋关节和膝关节置换术后假体周围感染的预期经济负担。
J Arthroplasty. 2021 May;36(5):1484-1489.e3. doi: 10.1016/j.arth.2020.12.005. Epub 2020 Dec 9.
2
Extended trochanteric osteotomy: improving the access and reducing the risk in revision THA.大转子延长截骨术:改善翻修全髋关节置换术的手术入路并降低风险
EFORT Open Rev. 2020 Feb 26;5(2):104-112. doi: 10.1302/2058-5241.5.190005. eCollection 2020 Feb.
3
Complications of Resection Arthroplasty in Two-Stage Revision for the Treatment of Periprosthetic Hip Joint Infection.
两阶段翻修治疗人工髋关节周围感染中切除关节成形术的并发症
J Clin Med. 2019 Dec 16;8(12):2224. doi: 10.3390/jcm8122224.
4
Hip and Knee Section, Prevention, Surgical Technique: Proceedings of International Consensus on Orthopedic Infections.髋膝关节部分、预防、手术技术:骨科感染国际共识会议论文集
J Arthroplasty. 2019 Feb;34(2S):S301-S307. doi: 10.1016/j.arth.2018.09.015. Epub 2018 Oct 19.
5
The operation of the century: total hip replacement.世纪手术:全髋关节置换术。
Lancet. 2007 Oct 27;370(9597):1508-19. doi: 10.1016/S0140-6736(07)60457-7.