Department of Orthopedic Surgery, Koenig-Ludwig-Haus, University of Wuerzburg, Brettreichstraße 11, 97074, Wuerzburg, Germany.
Hospital for Special Surgery, 525 East 71st Street, 10021, New York, NY, USA.
Oper Orthop Traumatol. 2023 Jun;35(3-4):135-145. doi: 10.1007/s00064-023-00801-1. Epub 2023 May 3.
Two-stage exchange with an antibiotic-loaded polymethylmethacrylate (PMMA) spacer is standard treatment for chronic periprosthetic joint infection of the shoulder. We present a safe and simple technique for patient-specific spacer implants.
(Chronic) periprosthetic joint infection of the shoulder.
Known allergy against components of PMMA bone cements. Inadequate compliance for two-stage exchange. Patient is unfit to undergo two-stage exchange.
Hardware removal, histologic and microbiologic samples, and debridement. Preparation of targeted or calculated antibiotic-loaded PMMA. Tailoring of patient-specific spacer. Spacer implantation.
Rehabilitation protocol. Antibiotic treatment. Reimplantation after successful eradication of infection.
两阶段关节置换术联合抗生素负载型聚甲基丙烯酸甲酯（PMMA） spacer 是治疗慢性肩人工关节周围感染的标准方法。我们提出了一种安全且简单的个体化 spacer 植入技术。
（慢性）肩人工关节周围感染。
已知对 PMMA 骨水泥成分过敏。无法遵行两阶段置换术。不适合行两阶段置换术。
移除硬件，获取组织学和微生物样本，清创。制备靶向或计算型抗生素负载型 PMMA。个体化定制 spacer。植入 spacer。
康复方案。抗生素治疗。成功清除感染后再次植入。
