COVID-19 与慢性肾脏病患者：巴西关注变异株相关的 2 年发病率和死亡率研究。
COVID-19 in patients with chronic kidney disease: a 2-year study of incidence and mortality in relation to the variants of concern waves in Brazil.
机构信息
Diagnosis and Therapy of Infectious Diseases and Cancer, Rene Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ), 1715 Augusto de Lima Avenue, Belo Horizonte, Minas Gerais, 30190-002, Brazil.
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens, Georgia, 30602-7387, USA.
出版信息
Trans R Soc Trop Med Hyg. 2023 Aug 3;117(8):606-608. doi: 10.1093/trstmh/trad019.
BACKGROUND
Chronic kidney disease (CKD) is a risk factor for severe coronavirus disease (COVID-19). In Brazil, the disease is the 10th highest cause of death. We evaluated the epidemiological impact of COVID-19 in CDK and non-CDK patients.
METHODS
Positive patients for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from 2020 to 2022 were classified according to the severity of COVID-19 and the numbers of cases and deaths were correlated to each wave of SARS-CoV-2 variants in Brazil.
RESULTS
We compared all variables, and our data show that CDK significantly increased the mortality rate among patients, especially before COVID-19 vaccination, in comparison with non-CKD patients.
CONCLUSIONS
CKD patients had a significantly increased mortality rate compared with non-CKD.
背景
慢性肾脏病（CKD）是严重冠状病毒病（COVID-19）的一个危险因素。在巴西，该病是第十大死亡原因。我们评估了 COVID-19 在 CKD 和非 CKD 患者中的流行病学影响。
方法
对 2020 年至 2022 年间严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）呈阳性的患者进行分类，根据 COVID-19 的严重程度以及病例和死亡人数与巴西 SARS-CoV-2 变异株的每一波相关联。
结果
我们比较了所有变量，我们的数据表明，与非 CKD 患者相比，CKD 显著增加了患者的死亡率，尤其是在 COVID-19 疫苗接种之前。
结论
与非 CKD 患者相比，CKD 患者的死亡率显著增加。
Zotero 插件