Department of Dermatology and STD, Meditouch Skin and Hair Clinic, Pokhara, Nepal.
Department of Dermatology and Venereology, BP Koirala Institute of Health Sciences, Dharan, Nepal.
Kathmandu Univ Med J (KUMJ). 2022 Jul-Sep;20(79):268-272.
Background Hirsutism is excess terminal hair growth in women at androgen-dependent sites of the body and it has great impact on psychological and social aspects of their lives, thus affecting their quality of life (QoL). Several studies assessing the quality of life in hirsute women could be found in world literature but none in Nepalese literature. So, this study was undertaken for the assessment of the impact of hirsutism on the quality of life in Nepalese women. Objective To assess the effect of hirsutism on quality of life of women in a tertiary center of Eastern Nepal and its association with various socio-demographic and clinical parameters. Method A cross-sectional questionnaire-based study was conducted in 49 participants aged 10 to 49 years at the Department of Dermatology, B.P. Koirala Institute of Health Sciences. Clinically diagnosed hirsute females with modified Ferriman-Gallwey (mFG) score > 8, were enrolled and asked to fill Dermatology Life Quality Index (DLQI) questionnaire in the Nepalese version. Result More than 57.2% of the study population was of age 20 to 29 years with a mean of 27.76±8.08 years. The mean Dermatology Life Quality Index score was 7.78±4.95. The moderate effect was seen in the majority of participants (36.7%) with a predominant effect upon aspects of life like daily activities and symptoms and feelings. Participants with higher mF-G score (22.15±3.82) had a very large effect on their quality of life. Younger unmarried women with a school education and having a longer duration of hirsutism were found to have a higher effect upon their quality of life. However, the association was not statistically significant. Conclusion Hirsutism had affected the quality of life moderately with predominant effect upon aspects like daily activities and symptoms and feelings. No significant association was elicited between severity of hirsutism and its effect on quality of life from our study.
多毛症是女性在雄激素依赖部位的过度终毛生长，对她们的生活心理和社会方面有很大影响，从而影响她们的生活质量（QoL）。在世界文献中可以找到一些评估多毛症妇女生活质量的研究，但在尼泊尔文献中没有。因此，本研究旨在评估多毛症对尼泊尔妇女生活质量的影响。
评估东部尼泊尔一家三级中心多毛症对妇女生活质量的影响及其与各种社会人口统计学和临床参数的关系。
在 B.P. Koirala 健康科学研究所皮肤科进行了一项基于问卷的横断面研究，共纳入 49 名年龄在 10 至 49 岁的临床诊断为多毛症的女性，改良 Ferriman-Gallwey（mFG）评分>8 分。让她们填写尼泊尔版皮肤病生活质量指数（DLQI）问卷。
研究人群中超过 57.2%的年龄在 20 至 29 岁之间，平均年龄为 27.76±8.08 岁。平均皮肤病生活质量指数（DLQI）得分为 7.78±4.95。大多数参与者（36.7%）存在中度影响，日常生活和症状及感受方面影响较大。mF-G 评分较高（22.15±3.82）的参与者对生活质量的影响非常大。年轻、未婚、接受过学校教育、多毛症持续时间较长的女性，对生活质量的影响较大。然而，这种关联没有统计学意义。
多毛症对生活质量有中度影响，对日常生活和症状及感受方面影响较大。本研究未发现多毛症严重程度与其对生活质量的影响之间存在显著关联。
