Department of Pathology, B and B Hospital, Gwarko, Lalitpur, Nepal.
Kathmandu Univ Med J (KUMJ). 2022 Jul-Sep;20(79):388-390.
Tuberculosis of central nervous system accounts for only 1% of tuberculosis cases worldwide, of which pituitary is an extremely unusual site. We report a case of pituitary tuberculosis in a 29-year-old female presenting with complains of headache and diminished vision on right eye. It was misdiagnosed as pituitary adenoma on radiology. Biopsy showed epithelioid granulomas, langhans giant cells and caseous necrosis. Ziehl nelseen stain showed presence of acid fast bacilli confirming the tubercular etiology. Therefore, histology remains the mainstay for diagnosis of these lesions. Early diagnosis and prompt use of antitubercular drugs results in good outcome.
中枢神经系统结核占全球结核病例的 1%,其中垂体是一个极其罕见的部位。我们报告了一例 29 岁女性垂体结核病例,表现为头痛和右眼视力下降。影像学检查误诊为垂体腺瘤。活检显示上皮样肉芽肿、朗汉斯巨细胞和干酪样坏死。齐-尼染色显示有抗酸杆菌,证实为结核病因。因此,组织学仍然是这些病变诊断的主要依据。早期诊断和及时使用抗结核药物可获得良好的结果。