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全身免疫炎症指数预测冷冻消融术后心房颤动复发的效果。

Effectiveness of the systemic immune inflammation index to predict atrial fibrillation recurrence after cryoablation.

机构信息

Department of Cardiology, University of Health Sciences, Ankara City Hospital, Ankara, 06800, Turkey.

Department of Cardiology, Medipol University, Bahçelievler Medipol Hospital, İstanbul, 34196, Turkey.

出版信息

Biomark Med. 2023 Jan;17(2):101-109. doi: 10.2217/bmm-2022-0515. Epub 2023 Apr 12.

Abstract

We aimed to investigate the predictive role of systemic immune inflammation index (SII) on atrial fibrillation (AF) recurrence following cryoballoon-based AF ablation. A total of 370 consecutive patients with symptomatic AF who underwent cryoablation were enrolled. The patients were divided into two groups according to recurrence development. During the follow-up period of 25.0 ± 6.7 months, recurrence was observed in 77 patients (20.8%). Receiver operating characteristic analysis demonstrated that using a cutoff level of 532, SII had a sensitivity of 71% and specificity of 68%. In the multivariate Cox model, high SII was a significant predictor of the recurrence. This study showed that higher SII level is an independent predictor of AF recurrence.

摘要

我们旨在研究基于冷冻球囊的房颤消融术后全身免疫炎症指数(SII)对房颤(AF)复发的预测作用。共纳入 370 例接受冷冻消融的有症状 AF 连续患者。根据复发情况将患者分为两组。在 25.0±6.7 个月的随访期间,77 例患者(20.8%)复发。受试者工作特征分析表明,使用 532 的截断值,SII 的敏感性为 71%,特异性为 68%。多变量 Cox 模型显示,高 SII 是复发的显著预测因子。这项研究表明,较高的 SII 水平是 AF 复发的独立预测因子。

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