The importance of inflammation in atrial fibrillation recurrence in patients with atrial fibrillation treated with Cryo balloon ablation.

AIM/BACKGROUND: Although atrial fibrillation is the most common rhythm problem, the results of treatment to restore sinus rhythm are still not satisfactory. Nearly half of patients undergoing ablation relapse within one year. Therefore, triggered activities may not be the only cause. Inflammation is quite common in AF. In this study, we investigated the effect of PIV, an inflammatory marker, on recurrence.

METHODS

A total of 157 patients who underwent ablation with cryo balloon were included in the study. One-year follow-up was evaluated for causes of recurrence.

RESULTS

When the inflammatory parameters between the two groups are analyzed, CRP (5.9 [5.0-6.9] vs 9.7 [7.6-11.9], p < 0.001), NL ratio (2.8 [2.5-3.0] vs 6.4 [5.0-6.8], p < 0.001), SII2 (618.5 [557.1-679.9] vs 1798.9 [1305.8-2292.1], p < 0.001), PIV (355.9 [313.4-398.4] vs 1832 [1317.8-2347.1], p < 001) were significantly higher in the AF recurrence group. ROC analysis showed that PIV had the best sensitivity and specificity.

CONCLUSIONS

Inflammation has been found to be a cause of AF recurrence and PIV is one of the best markers for this.