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抗菌手套技术现状的批判性回顾:进展、挑战与未来展望。

A critical review on the current state of antimicrobial glove technologies: advances, challenges and future prospects.

机构信息

Biofunctional Molecule Exploratory Research Group, School of Pharmacy, Monash University Malaysia, Selangor Darul Ehsan, Malaysia.

Department of Chemical Engineering, School of Engineering, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor, Malaysia.

出版信息

J Hosp Infect. 2023 Jul;137:24-34. doi: 10.1016/j.jhin.2023.03.022. Epub 2023 Apr 10.

Abstract

Following recent viral outbreaks, there has been a significant increase in global demand for gloves. Biomedical research focuses increasingly on antimicrobial gloves to combat microbial transmission and hospital-acquired infections. Most antimicrobial gloves are manufactured using antimicrobial chemicals such as disinfectants, biocides and sanitizers. The design of antimicrobial gloves incorporates advanced technologies, including colloidal particles and nanomaterials, to enhance antimicrobial effectiveness. A category of antimicrobial gloves also explores and integrates natural antimicrobial benefits from animals, plants and micro-organisms. Many types of antimicrobial agents are available; however, it is crucial that the selected agent exhibits a broad spectrum of activity and is not susceptible to promoting resistance. Additionally, future research should focus on the potential effect of antimicrobial gloves on the skin microbiota and irritation during extended wear. Careful integration of the antimicrobial agent is essential to ensure optimal effectiveness without compromising the mechanical properties of the gloves.

摘要

最近的病毒爆发后,手套的全球需求显著增加。生物医学研究越来越关注抗菌手套,以对抗微生物传播和医院获得性感染。大多数抗菌手套是使用抗菌化学品制造的,如消毒剂、杀生剂和防腐剂。抗菌手套的设计采用了先进的技术,包括胶体颗粒和纳米材料,以提高抗菌效果。抗菌手套的一个类别还探索并整合了来自动物、植物和微生物的天然抗菌益处。有许多类型的抗菌剂可供选择;然而,关键是所选的抗菌剂应具有广谱活性,并且不易产生抗药性。此外,未来的研究应侧重于抗菌手套在长时间佩戴时对皮肤微生物群和刺激的潜在影响。谨慎地整合抗菌剂对于确保在不损害手套机械性能的情况下实现最佳效果至关重要。

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