• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

N-氨甲酰谷氨酸在反刍动物生产中的意义。

The significance of N-carbamoylglutamate in ruminant production.

作者信息

McCoard Susan A, Pacheco David

机构信息

AgResearch Limited, Grasslands Research Centre, Tennent Drive, Private Bag 11008, Palmerston North, 4442, New Zealand.

出版信息

J Anim Sci Biotechnol. 2023 Apr 13;14(1):48. doi: 10.1186/s40104-023-00854-z.

DOI:10.1186/s40104-023-00854-z
PMID:37046347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10100185/
Abstract

Improving the efficiency and production of grazing ruminants to support food and fiber production, while reducing the environmental footprint and meeting the welfare needs of the animals, is important for sustainable livestock production systems. Development of new technologies that can improve the efficiency of nitrogen (N) utilization in ruminants, and that are effective and safe, has important implications for ruminant livestock production. N-carbomoylglutamate (NCG) is a functional micronutrient that stimulates endogenous synthesis of arginine, which can improve survival, growth, lactation, reproductive performance, and feed efficiency in mammals. There is a growing body of evidence to support the potential of dietary NCG supplementation to improve the productive capacity and N utilization efficiency of ruminants. This review summarizes the current literature on the effects of dietary supplementation with NCG in ruminants and impacts on production and potential to reduce the environmental footprint of farmed ruminant livestock. The current literature highlights the potential for commercial application in ruminant livestock to improve productivity and N utilization efficiency.

摘要

提高放牧反刍动物的效率和产量以支持食物和纤维生产,同时减少环境足迹并满足动物的福利需求,对可持续畜牧生产系统至关重要。开发能够提高反刍动物氮(N)利用效率、有效且安全的新技术,对反刍动物畜牧生产具有重要意义。N-氨甲酰谷氨酸(NCG)是一种功能性微量营养素,可刺激精氨酸的内源性合成,从而提高哺乳动物的存活率、生长、泌乳、繁殖性能和饲料效率。越来越多的证据支持日粮添加NCG可提高反刍动物生产能力和氮利用效率的潜力。本文综述了当前关于日粮添加NCG对反刍动物的影响及其对养殖反刍动物生产和减少环境足迹潜力的文献。当前文献强调了NCG在反刍动物畜牧中商业应用以提高生产力和氮利用效率的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6dd/10100185/731e0f0db8a7/40104_2023_854_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6dd/10100185/d477d245cc78/40104_2023_854_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6dd/10100185/731e0f0db8a7/40104_2023_854_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6dd/10100185/d477d245cc78/40104_2023_854_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6dd/10100185/731e0f0db8a7/40104_2023_854_Fig2_HTML.jpg

相似文献

1
The significance of N-carbamoylglutamate in ruminant production.N-氨甲酰谷氨酸在反刍动物生产中的意义。
J Anim Sci Biotechnol. 2023 Apr 13;14(1):48. doi: 10.1186/s40104-023-00854-z.
2
Effect of dietary N-carbamoylglutamate on milk production and nitrogen utilization in high-yielding dairy cows.日粮N-氨甲酰谷氨酸对高产奶牛产奶性能及氮利用的影响
J Dairy Sci. 2014;97(4):2338-45. doi: 10.3168/jds.2013-7330. Epub 2014 Jan 31.
3
BOARD-INVITED REVIEW: Quantifying water use in ruminant production.特邀综述:反刍动物生产中的用水量化
J Anim Sci. 2017 May;95(5):2001-2018. doi: 10.2527/jas.2017.1439.
4
Review: Optimizing ruminant conversion of feed protein to human food protein.综述:优化反刍动物饲料蛋白向人类食物蛋白的转化。
Animal. 2018 Aug;12(8):1722-1734. doi: 10.1017/S1751731117002592. Epub 2017 Nov 20.
5
Potential role of N-carbamoyl glutamate in biosynthesis of arginine and its significance in production of ruminant animals.N- 碳酰谷氨酸在精氨酸生物合成中的潜在作用及其在反刍动物生产中的意义。
J Anim Sci Biotechnol. 2013 Apr 10;4(1):16. doi: 10.1186/2049-1891-4-16.
6
Current available strategies to mitigate greenhouse gas emissions in livestock systems: an animal welfare perspective.畜牧系统中减轻温室气体排放的现有策略:动物福利视角
Animal. 2017 Feb;11(2):274-284. doi: 10.1017/S1751731116001440. Epub 2016 Jul 13.
7
Role of ruminant livestock in sustainable agricultural systems.反刍家畜在可持续农业系统中的作用。
J Anim Sci. 1996 Jun;74(6):1406-9. doi: 10.2527/1996.7461406x.
8
Breeding animals to feed people: The many roles of animal reproduction in ensuring global food security.养殖动物以养活人类:动物繁殖在确保全球粮食安全方面的多种作用。
Theriogenology. 2020 Jul 1;150:27-33. doi: 10.1016/j.theriogenology.2020.01.041. Epub 2020 Jan 20.
9
Invited review: Nitrogen in ruminant nutrition: A review of measurement techniques.邀请评论:反刍动物营养中的氮:测量技术综述。
J Dairy Sci. 2019 Jul;102(7):5811-5852. doi: 10.3168/jds.2018-15829. Epub 2019 Apr 25.
10
Dietary supplementation with N-carbamoylglutamate initiated from the prepartum stage improves lactation performance of postpartum dairy cows.从产前阶段开始补充N-氨甲酰谷氨酸可提高产后奶牛的泌乳性能。
Anim Nutr. 2021 Mar;7(1):232-238. doi: 10.1016/j.aninu.2020.07.002. Epub 2020 Oct 22.

引用本文的文献

1
Glucogenic Precursor Release from Dietary Supply Is a Potential Amplifier of Monosodium-Glutamate Ovary Stimuli in Sheep with Low Involving Key Gene Mediators of the Glutamate Pathway.从饮食供应中释放生糖前体是低谷氨酸途径关键基因介导的绵羊中味精卵巢刺激的潜在放大器。
Animals (Basel). 2025 Aug 11;15(16):2345. doi: 10.3390/ani15162345.
2
β-Alanine decreases plasma taurine but improves nitrogen utilization efficiency in beef steers.β-丙氨酸可降低肉牛血浆中的牛磺酸水平,但能提高其氮利用效率。
Anim Nutr. 2025 Jun 6;22:50-60. doi: 10.1016/j.aninu.2025.05.001. eCollection 2025 Sep.
3
Metabolism and Nutrition of L-Glutamate and L-Glutamine in Ruminants.

本文引用的文献

1
-Carbamylglutamate and l-arginine supplementation improve hepatic antioxidant status in intrauterine growth-retarded suckling lambs.补充氨基甲酰谷氨酸和L-精氨酸可改善宫内生长受限哺乳羔羊的肝脏抗氧化状态。
RSC Adv. 2020 Mar 18;10(19):11173-11181. doi: 10.1039/c9ra09316h. eCollection 2020 Mar 16.
2
-Carbamoylglutamate Supplementation on the Digestibility, Rumen Fermentation, Milk Quality, Antioxidant Parameters, and Metabolites of Jersey Cattle in High-Altitude Areas.添加氨甲酰谷氨酸对高海拔地区泽西牛消化率、瘤胃发酵、牛奶品质、抗氧化参数及代谢产物的影响
Front Vet Sci. 2022 Apr 4;9:848912. doi: 10.3389/fvets.2022.848912. eCollection 2022.
3
反刍动物中L-谷氨酸和L-谷氨酰胺的代谢与营养
Animals (Basel). 2024 Jun 14;14(12):1788. doi: 10.3390/ani14121788.
4
The Effect of N-Carbamylglutamate Supplementation during the Last Third of Gestation on the Growth and Development of Fetuses Born to Nutrient-Restricted Twin-Bearing Ewes.妊娠后期补充N-氨甲酰谷氨酸对营养受限的双胎妊娠母羊所产胎儿生长发育的影响。
Animals (Basel). 2024 Mar 19;14(6):946. doi: 10.3390/ani14060946.
5
Benzoic acid supplementation improves the growth performance, nutrient digestibility and nitrogen metabolism of weaned lambs.补充苯甲酸可改善断奶羔羊的生长性能、养分消化率和氮代谢。
Front Vet Sci. 2024 Feb 9;11:1351394. doi: 10.3389/fvets.2024.1351394. eCollection 2024.
Effects of dietary supplementation with N-carbamylglutamate on maternal endometrium and fetal development during early pregnancy in Inner Mongolia white cashmere goats.
N- 氨甲酰谷氨酸对内蒙古白绒山羊妊娠早期母体子宫内膜和胎儿发育的影响。
Anim Sci J. 2022 Jan-Dec;93(1):e13693. doi: 10.1111/asj.13693.
4
Dietary -carbamylglutamate or L-arginine improves fetal intestinal amino acid profiles during intrauterine growth restriction in undernourished ewes.饮食中的氨甲酰谷氨酸或L-精氨酸可改善营养不良母羊子宫内生长受限期间胎儿肠道的氨基酸谱。
Anim Nutr. 2022 Mar;8(1):341-349. doi: 10.1016/j.aninu.2021.12.001. Epub 2021 Dec 27.
5
Effects of Inclusion of -Carbamylglutamate in the Non-Protein Diet on Growth and Slaughter Performance, Meat Quality, Nitrogen Metabolism and Antioxidant of Holstein Bulls.在非蛋白日粮中添加γ-氨基甲酰谷氨酸对荷斯坦公牛生长性能、屠宰性能、肉品质、氮代谢及抗氧化性能的影响
Animals (Basel). 2021 Dec 24;12(1):33. doi: 10.3390/ani12010033.
6
L-Arginine Nutrition and Metabolism in Ruminants.反刍动物的 L-精氨酸营养与代谢。
Adv Exp Med Biol. 2022;1354:177-206. doi: 10.1007/978-3-030-85686-1_10.
7
Supplementing -carbamoylglutamate in late gestation increases newborn calf weight by enhanced placental expression of mTOR and angiogenesis factor genes in dairy cows.妊娠后期补充氨甲酰谷氨酸可通过增强奶牛胎盘mTOR和血管生成因子基因的表达来增加新生犊牛体重。
Anim Nutr. 2021 Dec;7(4):981-988. doi: 10.1016/j.aninu.2021.05.007. Epub 2021 Sep 28.
8
Dietary N-carbamylglutamate or l-arginine supplementation improves hepatic energy status and mitochondrial function and inhibits the AMP-activated protein kinase-peroxisome proliferator-activated receptor γ coactivator-1α-transcription factor A pathway in intrauterine-growth-retarded suckling lambs.日粮补充N-氨甲酰谷氨酸或L-精氨酸可改善宫内生长受限哺乳羔羊的肝脏能量状态和线粒体功能,并抑制AMP激活的蛋白激酶-过氧化物酶体增殖物激活受体γ共激活因子-1α-转录因子A通路。
Anim Nutr. 2021 Sep;7(3):859-867. doi: 10.1016/j.aninu.2021.02.005. Epub 2021 Jul 14.
9
Placental adaptation to maternal malnutrition.胎盘对母体营养不良的适应。
Reproduction. 2021 Sep 9;162(4):R73-R83. doi: 10.1530/REP-21-0179.
10
Review: An overview of beef production from pasture and feedlot globally, as demand for beef and the need for sustainable practices increase.综述:随着对牛肉的需求增加和对可持续生产实践的需求增加,全球牧场和饲料场的牛肉生产概述。
Animal. 2021 Dec;15 Suppl 1:100295. doi: 10.1016/j.animal.2021.100295. Epub 2021 Jul 15.