多功能赖氨酰氧化酶。
Multifunctional Lysyl Oxidases.
机构信息
The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.
出版信息
Int J Mol Sci. 2023 Mar 23;24(7):6044. doi: 10.3390/ijms24076044.
Abstract
This Special Issue on lysyl oxidases, which are proteins derived from five related genes known as , and -, brings together articles that reflect some of the diverse approaches and perspectives needed to better understand the biology of these multifunctional proteins [...].
摘要
本关于赖氨酰氧化酶的特刊，这些蛋白来源于五个相关基因，被称为、、、和 ，汇集了一些反映更好地理解这些多功能蛋白的生物学所需的不同方法和观点的文章。
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Multifunctional Lysyl Oxidases.多功能赖氨酰氧化酶。
Int J Mol Sci. 2023 Mar 23;24(7):6044. doi: 10.3390/ijms24076044.
2
Purification of enzymatically active human lysyl oxidase and lysyl oxidase-like protein from Escherichia coli inclusion bodies.从大肠杆菌包涵体中纯化具有酶活性的人赖氨酰氧化酶和类赖氨酰氧化酶蛋白。
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Lysyl oxidases in mammalian development and certain pathological conditions.赖氨酰氧化酶在哺乳动物发育及某些病理状况中的作用
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Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts.赖氨酰氧化酶表达的扰动广泛影响肺成纤维细胞的转录组。
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The possibilities of LOXL4 as a prognostic marker for carcinomas.LOXL4 作为癌预后标志物的可能性。
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6
Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation.剥脱综合征中房水赖氨酰氧化酶活性与转化生长因子-β水平及赖氨酰氧化酶样蛋白1基因型的相关性
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Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes.表皮角质形成细胞在细胞黏附和终末分化过程中LOX和LOXL2表达的相互调节。
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Lysyl oxidase and the lysyl oxidase-like protein modulate odontoblastic differentiation of human dental pulp cells.赖氨酰氧化酶和赖氨酰氧化酶样蛋白调节人牙髓细胞的成牙本质细胞分化。
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Evolving roles of lysyl oxidase family in tumorigenesis and cancer therapy.赖氨酰氧化酶家族在肿瘤发生和癌症治疗中的作用不断演变。
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A new role for LOX and LOXL2 proteins in transcription regulation.赖氨氧化酶（LOX）和赖氨氧化酶样蛋白2（LOXL2）在转录调控中的新作用。
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The dual role of LOXL4 in the pathogenesis and development of human malignant tumors: a narrative review.赖氨酰氧化酶样蛋白4（LOXL4）在人类恶性肿瘤发病机制及发展中的双重作用：一篇综述
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本文引用的文献
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Insight into the Spatial Arrangement of the Lysine Tyrosylquinone and Cu in the Active Site of Lysyl Oxidase-like 2.深入了解赖氨酰氧化酶样 2 活性位点中天冬氨酸酪氨酸醌和铜的空间排列。
Int J Mol Sci. 2022 Nov 12;23(22):13966. doi: 10.3390/ijms232213966.
2
A 3D-Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase-Like 2.赖氨酸氧化酶样蛋白 2 的胺氧化酶结构域的 3D 预测结构。
Int J Mol Sci. 2022 Nov 2;23(21):13385. doi: 10.3390/ijms232113385.
3
Lysyl Oxidase Family Proteins: Prospective Therapeutic Targets in Cancer.赖氨酰氧化酶家族蛋白：癌症的潜在治疗靶点。
Int J Mol Sci. 2022 Oct 14;23(20):12270. doi: 10.3390/ijms232012270.
4
Lysyl Oxidases: Orchestrators of Cellular Behavior and ECM Remodeling and Homeostasis.赖氨酰氧化酶：细胞行为、细胞外基质重塑和动态平衡的协调者。
Int J Mol Sci. 2022 Sep 27;23(19):11378. doi: 10.3390/ijms231911378.
5
Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes.敲除五个赖氨酰氧化酶家族基因可鉴定赖氨酰氧化酶原酶调控的基因。
Int J Mol Sci. 2022 Sep 26;23(19):11322. doi: 10.3390/ijms231911322.
6
Mass Spectrometry-Based Disulfide Mapping of Lysyl Oxidase-like 2.基于质谱的赖氨酰氧化酶样蛋白 2 的二硫键图谱分析。
Int J Mol Sci. 2022 May 24;23(11):5879. doi: 10.3390/ijms23115879.
7
Loxl2 and Loxl3 Paralogues Play Redundant Roles during Mouse Development.Loxl2 和 Loxl3 基因在小鼠发育过程中发挥冗余作用。
Int J Mol Sci. 2022 May 20;23(10):5730. doi: 10.3390/ijms23105730.
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Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis.泛赖氨酸氧化酶抑制剂 PXS-5505 通过抑制系统性硬化症啮齿动物模型中的胶原交联改善多器官纤维化。
Int J Mol Sci. 2022 May 16;23(10):5533. doi: 10.3390/ijms23105533.
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Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy.赖氨酰氧化酶加工在癌症和眼部疾病中的功能和机制，重点关注糖尿病视网膜病变。
Int J Mol Sci. 2022 May 3;23(9):5088. doi: 10.3390/ijms23095088.
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Cleavage of LOXL1 by BMP1 and ADAMTS14 Proteases Suggests a Role for Proteolytic Processing in the Regulation of LOXL1 Function.BMP1 和 ADAMTS14 蛋白酶对 LOXL1 的裂解表明蛋白水解处理在 LOXL1 功能调节中的作用。
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