Butt A D
S Afr Med J. 1986 May 24;69(11):677-80.
Recovery time after ultrabrief anaesthesia for minor gynaecological procedures was shown to be significantly and appreciably longer after thiopentone induction than after Althesin (alphaxalone and alphadolone), etomidate or propanidid. Suitable anaesthesia was provided by all techniques, but propanidid is associated with a 51% rise in pulse rate and etomidate with an 18% slowing. Twenty-seven per cent of patients anaesthetized with propanidid or etomidate were nauseous or vomited immediately postoperatively. Oxytocin 5 U given as an intravenous bolus for uterine contraction markedly increased heart rate (+ 29%). Althesin is now excluded on the basis of occasional adverse reactions; none of the techniques used is entirely satisfactory.
对于小型妇科手术,硫喷妥钠诱导后的超短效麻醉恢复时间明显长于阿耳忒辛(α-羟孕酮和α-羟孕二酮)、依托咪酯或丙泮尼地诱导后的恢复时间。所有技术均能提供合适的麻醉效果,但丙泮尼地会使脉搏率升高51%,依托咪酯会使脉搏率减慢18%。使用丙泮尼地或依托咪酯麻醉的患者中有27%在术后立即出现恶心或呕吐。静脉推注5单位缩宫素用于子宫收缩会使心率显著增加(+29%)。由于偶尔会出现不良反应,现在已不再使用阿耳忒辛;所使用的技术均不完全令人满意。