Clinic of Dermatology, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy.
Hospital Cardiology and UTIC, Ospedali Riuniti di Ancona, 60126 Ancona, Italy.
Nutrients. 2023 Mar 31;15(7):1705. doi: 10.3390/nu15071705.
Psoriasis is an immune-mediated inflammatory systemic disease with skin tropism and chronic relapsing course; it is associated with an increased cardiovascular risk and with many metabolic comorbidities, emerging during childhood in 22-33% of cases. Diet influences the presentation and the clinical course of inflammatory diseases, including psoriasis; in particular, it was shown that a Mediterranean, gluten-free, or low-calorie diet may positively affect disease control in adult patients with psoriasis and adequate pharmacological therapy. These three dietary regimens may play a role also in children with psoriasis. It has been demonstrated that pediatric psoriasis is associated with psychological stress, celiac disease, and obesity, which may be positively influenced by these dietary regimens, respectively. Therefore, the expertise of multiple health figures (gastroenterologists, nutritionists, pediatricians, dermatologists) is required to plan a tailor-made dietary strategy, ensuring good growth, through an adequate intake of essential micro- and macronutrients and, at the same time, impacting the pro-inflammatory biochemical profile and on the associated cardiovascular risk of psoriasis disease.
银屑病是一种具有皮肤嗜性和慢性复发性的免疫介导的炎症性系统性疾病；它与心血管风险增加以及许多代谢合并症相关，在 22-33%的病例中在儿童时期出现。饮食会影响包括银屑病在内的炎症性疾病的表现和临床过程；特别地，已经表明地中海饮食、无麸质饮食或低热量饮食可能会对接受适当药物治疗的成年银屑病患者的疾病控制产生积极影响。这三种饮食方案在患有银屑病的儿童中也可能发挥作用。已经证明，儿科银屑病与心理压力、乳糜泻和肥胖有关，这些饮食方案可能分别对其产生积极影响。因此，需要多个健康领域的专业知识（胃肠病学家、营养师、儿科医生、皮肤科医生）来制定量身定制的饮食策略，通过摄入足够的必需微量和宏量营养素来确保良好的生长，同时影响促炎的生化特征和银屑病疾病相关的心血管风险。
