Mary Ann Swetland Center for Environmental Health, Case Western Reserve University, Cleveland, OH 44106, USA.
Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH 44106, USA.
Nutrients. 2023 Apr 1;15(7):1731. doi: 10.3390/nu15071731.
Advancements in cancer treatments over the past several decades have led to improved cancer survival in adolescents and young adults (AYAs, ages 15-39 years). However, AYA cancer survivors are at an increased risk for "late effects", including cardiovascular, pulmonary and bone diseases as well as fatigue, infertility and secondary cancers. The treatments for cancer may also alter taste, lead to nutritional deficiencies and increase financial burdens that, when taken together, may increase the risk of food and nutrition security in AYA cancer survivors. Furthermore, although AYAs are often merged together in cancer survivorship studies, adolescents and young adults have distinct developmental, psychosocial and pathophysiological differences that may modify their risk of nutritional challenges. In this narrative review and "Call to Action", rationale is provided for why there is a need to better understand nutritional challenges and food insecurity in AYA cancer survivors as a special population. Then, recommendations for next steps to advance knowledge and policy in this field are provided. In particular, integrating screening for food and nutrition insecurity and enhancing awareness of existing resources (e.g., the Supplemental Nutrition Assistance Program, SNAP) might help AYA cancer survivors combat nutritional deficiencies and reduce late effects while improving their overall survival and quality of life.
过去几十年中,癌症治疗的进步使青少年和年轻成年人(AYA,年龄 15-39 岁)的癌症生存率得到提高。然而,AYA 癌症幸存者面临着“晚期效应”的风险增加,包括心血管、肺部和骨骼疾病以及疲劳、不孕和继发性癌症。癌症的治疗也可能改变味觉,导致营养缺乏,并增加经济负担,这些因素加在一起,可能会增加 AYA 癌症幸存者的食物和营养安全风险。此外,尽管 AYAs 在癌症生存研究中经常合并在一起,但青少年和年轻成年人在发育、心理社会和病理生理学方面存在明显的差异,这可能会改变他们面临营养挑战的风险。在这篇叙述性综述和“行动呼吁”中,提供了为什么需要更好地了解 AYA 癌症幸存者这一特殊群体的营养挑战和粮食不安全问题的理由。然后,为该领域的知识和政策提供了下一步的建议。特别是,通过整合对食物和营养不安全的筛查,并增强对现有资源(例如补充营养援助计划,SNAP)的认识,可能有助于 AYA 癌症幸存者克服营养缺乏,减少晚期效应,同时提高他们的总体生存率和生活质量。