[体内体细胞的细胞遗传学效应与辐射剂量及化学诱变暴露之间的关系：暴露持续时间和细胞选择的影响]
[Relation between the cytogenetic effect and the dose of radiation and chemical mutagenic exposure of somatic cells in vivo: effect of the duration of exposure and cell selection].
作者信息
Leonard A
出版信息
Tsitol Genet. 1986 Mar-Apr;20(2):115-21.
PMID:3705166
Abstract
Dose-response relationships obtained in vivo in mammalian cells or in vitro when studying structural chromosome aberrations in somatic cells may be used for monitoring human populations exposed to mutagenic agents. While the method appears of interest for biological dosimetry on people exposed to relatively high doses of ionizing radiation, its value for persons professionally exposed to chemicals is, however, limited.
摘要
在研究体细胞中的染色体结构畸变时，在哺乳动物细胞体内或体外获得的剂量-反应关系可用于监测接触诱变剂的人群。虽然该方法对于接触相对高剂量电离辐射的人群进行生物剂量测定似乎有意义，但其对于职业接触化学物质的人员的价值却很有限。
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