de Mascarel I, Trojani M, Coindre J M, Faucher A
Tumori. 1986 Apr 30;72(2):183-6. doi: 10.1177/030089168607200211.
Fourty-one patients underwent breast reconstruction after mastectomy for cancer and reduction plasty of the second breast, over a 36-month period. These plasties were performed only for reasons of asymmetry, in the absence of any positive preoperative finding. Histologic examination using semiserial sectioning of the whole excised sample detected a high frequency of unsuspected cancer 14/41 (34%). There was a strong predominance of in situ carcinomas 11/41 (27%) over invasive carcinomas 3/41 (7%). These results were compared with those of other bilateral cancer series. When such cancers were detected by random biopsies or mastectomies, the rate of in situ carcinomas was much greater than in cancers detected only by physical and mammographic examination.
在36个月的时间里，41例患者在因癌症行乳房切除术后进行了乳房重建以及对另一侧乳房进行了缩小整形术。这些整形手术仅出于不对称的原因进行，术前未发现任何阳性体征。对整个切除样本进行半连续切片的组织学检查发现，未被怀疑的癌症发生率很高，为14/41（34%）。原位癌占主导地位，为11/41（27%），高于浸润性癌3/41（7%）。这些结果与其他双侧癌症系列的结果进行了比较。当通过随机活检或乳房切除术检测到此类癌症时，原位癌的发生率远高于仅通过体格检查和乳房X线检查检测到的癌症。
