Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK.
Department of Brain Repair & Rehabilitation, Institute of Neurology, University College London, London, UK.
J R Coll Physicians Edinb. 2023 Jun;53(2):128-131. doi: 10.1177/14782715231168238. Epub 2023 Apr 13.
The experimental studies of David Ferrier (1843-1928), establishing many of the principles of cerebral localisation which still underpin neurological reasoning in clinical practice, were first reported 150 years ago. This paper briefly reviews Ferrier's experimental work, first undertaken in the laboratory at the West Riding Lunatic Asylum in Wakefield, West Yorkshire and his resulting publications of 1873, as well as some contemporaneous responses to his findings. These not only established 'motor centres' pertinent to physiology and the signs of cerebral disease but also, from the outset, had ramifications for Ferrier's understanding of higher mental functions. That linguistic, mnemonic and perceptual cognitive functions might be related to localised areas within the brain received its most emphatic initial impetus from Ferrier's work.
大卫·费里尔（David Ferrier，1843-1928 年）的实验研究确立了许多大脑定位的原则，这些原则至今仍是临床实践中神经推理的基础。他的这些实验研究报告于 150 年前。本文简要回顾了费里尔的实验工作，这些工作最初是在西约克郡韦克菲尔德的西赖丁疯人院的实验室进行的，以及他在 1873 年的相关出版物，还有一些同时代对他的发现的回应。这些发现不仅确立了与生理学和大脑疾病症状相关的“运动中心”，而且从一开始就对费里尔对更高层次心理功能的理解产生了影响。语言、记忆和感知认知功能可能与大脑的特定区域有关，这一观点最初最强烈的推动力来自于费里尔的工作。
