Fishman R S
Washington (DC) Hospital Center, USA.
Arch Neurol. 1995 Jul;52(7):725-30. doi: 10.1001/archneur.1995.00540310099022.
To review the work of David Ferrier (1843-1928), the British pioneer in the localization of function in the cerebral cortex. In his experiments on monkeys, Ferrier mistakenly located the center for vision in the angular gyrus of the parietal lobe. What led him to this error?
Ferrier included details of his technique and many of his original laboratory observations in his published papers and books; these published works have allowed a reconstruction of his thought processes as he struggled to assess vision in untrained animals.
The occipital lobe lesions produced by Ferrier did not yield vision defects that were gross enough to be detected by observing a monkey's random behavior. On the other hand, the posterior parietal lesions produced by Ferrier did change a monkey's behavior in ways in which Ferrier misinterpreted as being due to induced blindness. Ferrier had probably induced visual neglect and a disinclination in the monkey to move its body, as well as actual vision disturbances in guiding voluntary limb movements.
回顾英国大脑皮层功能定位先驱大卫·费里尔（1843 - 1928）的工作。在对猴子的实验中，费里尔错误地将视觉中枢定位在顶叶的角回。是什么导致他出现这一错误？
费里尔在其发表的论文和著作中包含了他的技术细节以及许多原始实验室观察结果；这些已发表的作品使我们能够重构他在努力评估未受过训练动物的视觉时的思维过程。
费里尔造成的枕叶损伤并未产生严重到足以通过观察猴子的随机行为检测到的视觉缺陷。另一方面，费里尔造成的顶叶后部损伤确实以费里尔误解为是由诱导性失明所致的方式改变了猴子的行为。费里尔可能诱发了猴子的视觉忽视、不愿移动身体的倾向，以及在引导自主肢体运动时的实际视觉障碍。
