未折叠蛋白反应的三剑客之间存在分歧。
Disagreement among the three musketeers of the unfolded protein response.
机构信息
Institute of Genetics, Biological Research Centre , Szeged, Hungary.
Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest, Hungary.
出版信息
J Cell Biol. 2023 May 1;222(5). doi: 10.1083/jcb.202304013. Epub 2023 Apr 13.
Abstract
Jipa and Juhász preview results from the lab of Tao Wang (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202208147) which show a surprising antagonism between two branches of the unfolded protein response that dictates disease progression in a model of autosomal dominant retinitis pigmentosa.
摘要
纪帕和尤哈斯提前浏览了陶旺（2023. 《细胞生物学杂志》.https://doi.org/10.1083/jcb.202208147）实验室的结果，这些结果表明在常染色体显性遗传性视网膜色素变性模型中，未折叠蛋白反应的两个分支之间存在令人惊讶的拮抗作用，这决定了疾病的进展。
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