两次 SARS-CoV-2 大流行后儿童多系统炎症综合征的发病率和临床表型：一项克罗地亚全国前瞻性研究。
Incidence and Clinical Phenotype of Multisystem Inflammatory Syndrome in Children After Two SARS-CoV-2 Pandemic Waves: A Croatian Prospective Nationwide Study.
机构信息
From the University Hospital for Infectious Diseases "Dr. Fran Mihaljević," Zagreb, Croatia.
Department for Infectious diseases, University of Zagreb, School of Medicine, Croatia.
出版信息
Pediatr Infect Dis J. 2023 Jul 1;42(7):e229-e231. doi: 10.1097/INF.0000000000003924. Epub 2023 Apr 4.
This prospective nationwide study in Croatia (March 1, 2020-December 31, 2021) embraced 121 children with multisystem inflammatory syndrome. Incidence rates, disease course and outcomes were similar to those reported from other European countries. The severe acute respiratory syndrome coronavirus 2 virus Alpha strain appeared associated with a higher propensity to result in multisystem inflammatory syndrome in children than the Delta strain but did not appear related to disease severity.
这项在克罗地亚进行的前瞻性全国性研究（2020 年 3 月 1 日至 2021 年 12 月 31 日）纳入了 121 例儿童多系统炎症综合征患者。其发病率、疾病过程和结局与来自其他欧洲国家的报告相似。与 Delta 变异株相比，严重急性呼吸综合征冠状病毒 2 病毒 Alpha 变异株似乎更易导致儿童多系统炎症综合征，但与疾病严重程度似乎无关。
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