Faculty of New Sciences and Technologies, Semnan University, P.O. Box 19111-35131, Semnan, Iran.
Department of Polyurethane and Advanced Materials, Iran Polymer & Petrochemical Institute, P.O. Box 14965-115, Tehran, Iran.
Int J Biol Macromol. 2023 Jun 30;241:124343. doi: 10.1016/j.ijbiomac.2023.124343. Epub 2023 Apr 11.
Tragacanth is an abundant natural gum extracted from some plants and is dried for use in various applications from industry to biomedicines. It is a cost-effective and easily accessible polysaccharide with desirable biocompatibility and biodegradability, drawing much attention for use in new biomedical applications such as wound healing and tissue engineering. Moreover, this anionic polysaccharide with a highly branched structure has been used as an emulsifier and thickening agent in pharmaceutical applications. In addition, this gum has been introduced as an appealing biomaterial for producing engineering tools in drug delivery. Furthermore, the biological properties of tragacanth gum have made it a favorable biomaterial in cell therapies, and tissue engineering. This review aims to discuss the recent studies on this natural gum as a potential carrier for different drugs and cells.
黄蓍胶是一种从某些植物中提取的丰富天然胶，经过干燥后可用于从工业到生物医学等各种应用。它是一种具有成本效益且易于获得的多糖，具有良好的生物相容性和生物降解性，因此在新的生物医学应用（如伤口愈合和组织工程）中备受关注。此外，这种具有高度支化结构的阴离子多糖已被用作药物制剂中的乳化剂和增稠剂。此外，这种胶已被引入作为用于药物输送的工程工具的有吸引力的生物材料。此外，黄蓍胶的生物学特性使其成为细胞治疗和组织工程中理想的生物材料。本综述旨在讨论关于这种天然胶作为不同药物和细胞的潜在载体的最新研究。
