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股骨颈系统与空心螺钉治疗股骨颈骨折的比较:系统评价和荟萃分析。

Comparison of femoral neck system versus cannulated screws for treatment of femoral neck fractures: a systematic review and meta-analysis.

机构信息

Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.

出版信息

BMC Musculoskelet Disord. 2023 Apr 13;24(1):285. doi: 10.1186/s12891-023-06378-x.

Abstract

BACKGROUND

Recently, some studies on the efficacy of the femoral neck system (FNS) in treating femoral neck fractures (FNFs) have been published. Therefore, a systematic review was performed to clarify the efficacy and safety of FNS versus cannulated screws (CS) for the treatment of FNFs.

METHOD

The PubMed, EMBASE, and Cochrane databases were systematically searched for studies comparing FNS and CS fixations in FNFs. Intraoperative indicators, postoperative clinical indicators, postoperative complications, and postoperative scores were compared between the implants.

RESULTS

A total of eight studies were included in the study, involving 448 FNFs patients. The results showed that patients in FNS group were significantly lower than the CS group in the number of X-ray exposures (WMD = -10.16; 95% CI, -11.44 to -8.88; P < 0.001; I = 0%), fracture healing time (WMD = -1.54; 95% CI, -2.38 to -0.70; P < 0.001; I = 92%), length of femoral neck shortening (WMD = -2.01; 95% CI, -3.11 to -0.91; P < 0.001; I = 0%), femoral head necrosis (OR = 0.27; 95% CI, 0.08 to 0.83; P = 0.02; I = 0%), implant failure/cutout (OR = 0.28; 95% CI, 0.10 to 0.82; P = 0.02; I = 0%), and Visual Analog Scale Score (WMD = -1.27; 95% CI, -2.51 to -0.04; P = 0.04; I = 91%). And the Harris Score was significantly higher in the FNS group than in the CS group (WMD = 4.15; 95% CI, 1.00 to 7.30; P = 0.01; I = 89%).

CONCLUSIONS

Based on this meta-analysis, FNS shows better clinical efficacy and safety in treating FNFs compared to CS. However, due to the limited quality and number of included studies and the high heterogeneity of the meta-analysis; large samples and multicenter RCTs are needed to confirm this conclusion in the future.

LEVEL OF EVIDENCE

II, Systematic review and Meta-analysis.

TRIAL REGISTRATION

PROSPERO CRD42021283646.

摘要

背景

最近,有一些关于股骨颈系统(FNS)治疗股骨颈骨折(FNFs)疗效的研究发表。因此,进行了一项系统评价,以明确 FNS 与空心螺钉(CS)治疗 FNFs 的疗效和安全性。

方法

系统检索 PubMed、EMBASE 和 Cochrane 数据库中比较 FNS 和 CS 固定治疗 FNFs 的研究。比较两种植入物的术中指标、术后临床指标、术后并发症和术后评分。

结果

共纳入 8 项研究,涉及 448 例 FNFs 患者。结果显示,FNS 组患者的 X 线曝光次数明显少于 CS 组(WMD=-10.16;95%CI,-11.44 至-8.88;P<0.001;I=0%)、骨折愈合时间(WMD=-1.54;95%CI,-2.38 至-0.70;P<0.001;I=92%)、股骨颈缩短长度(WMD=-2.01;95%CI,-3.11 至-0.91;P<0.001;I=0%)、股骨头坏死(OR=0.27;95%CI,0.08 至 0.83;P=0.02;I=0%)、植入物失败/穿出(OR=0.28;95%CI,0.10 至 0.82;P=0.02;I=0%)和视觉模拟评分(WMD=-1.27;95%CI,-2.51 至-0.04;P=0.04;I=91%)。FNS 组的 Harris 评分明显高于 CS 组(WMD=4.15;95%CI,1.00 至 7.30;P=0.01;I=89%)。

结论

基于这项荟萃分析,FNS 在治疗 FNFs 方面比 CS 具有更好的临床疗效和安全性。然而,由于纳入研究的质量和数量有限,以及荟萃分析的高度异质性,未来需要大样本和多中心 RCT 来证实这一结论。

证据水平

II,系统评价和荟萃分析。

试验注册

PROSPERO CRD42021283646。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8979/10099821/f51dc68a56be/12891_2023_6378_Fig1_HTML.jpg

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