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病例报告:表现为假性肠梗阻的结肠壁内印戒细胞癌:病例介绍及文献复习

Case Report: Intramural colonic signet ring cell carcinoma presenting as intestinal pseudo-obstruction: A case presentation and review of the literature.

作者信息

Li Yuxia, He Genmei, Zhong Ruqin, Li Xuejuan, Li Huamei, Dong Huaqiong, Zhang Yun, Zhao Guohong, Fang Leilei

机构信息

Department of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Department of Gastroenterology, People's Hospital, Lahu-Wa-Bulang-Dai Autonomous County of Shuangjiang, Lincang, Yunnan, China.

出版信息

Front Oncol. 2023 Mar 23;13:1059368. doi: 10.3389/fonc.2023.1059368. eCollection 2023.

Abstract

Colorectal cancer (CRC) is the third most common cancer in the world. Other than adenocarcinomas, exceptional tumors of the colon and rectum represent a neglected clinical issue due to their rarity. Signet ring cell carcinoma (SRCC) is a rare subtype of CRC and has an extremely poor prognosis due to its advanced stage at diagnosis. Here we report a rare case of colorectal SRCC manifested as recurrent intestinal obstruction with a negative colonoscopy. Finally, he was diagnosed with signet ring cell carcinoma of the colon by postoperative pathology. It emphasized the special feature of intramural tumor growth without penetrating the mucosa in SRCC, which requires timely surgical intervention to avoid delay in diagnosis and treatment.

摘要

结直肠癌(CRC)是全球第三大常见癌症。除腺癌外,结肠和直肠的特殊肿瘤因其罕见性而成为一个被忽视的临床问题。印戒细胞癌(SRCC)是CRC的一种罕见亚型,由于其在诊断时已处于晚期,预后极差。在此,我们报告一例罕见的结直肠SRCC病例,表现为反复肠梗阻且结肠镜检查结果为阴性。最终,他通过术后病理被诊断为结肠印戒细胞癌。这强调了SRCC壁内肿瘤生长而不穿透黏膜的特殊特征,这需要及时进行手术干预以避免诊断和治疗延误。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5868/10088906/a3dcf49071e2/fonc-13-1059368-g001.jpg

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