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盲肠原发性印戒细胞癌:一例罕见病例报告

Primary signet-ring cell carcinoma of the cecum: A rare case report.

作者信息

Anas Derkaoui, Tarik Deflaoui, Yassine Mabrouk Mohamed, Haitam Soussan, Ayoub Madani, Magouri Oumaima, Rachid Jabi, Mohammed Bouziane

机构信息

Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco.

Department of General Surgery, Mohamed VI University Hospital, Oujda, Morocco; Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation (LAMCESM), Mohammed 1st University, Oujda, Morocco.

出版信息

Int J Surg Case Rep. 2022 Sep;98:107466. doi: 10.1016/j.ijscr.2022.107466. Epub 2022 Jul 30.

DOI:10.1016/j.ijscr.2022.107466
PMID:35973320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9400076/
Abstract

INTRODUCTION AND IMPORTANCE

Primary SRCC is a rare histological colorectal cancer subtype. It is characterized by distinct clinical presentation.

CASE PRESENTATION

This case report describes a rare case of a Primary Signet-ring cell carcinoma of the cecum. A 37-year-old man came to the emergency department with bowel obstruction and altered general condition. The abdominal CT scan showed an intestinal occlusion upstream a thickening of the cecum. An exploratory laparotomy found a distention of the bowl with a suspect thickening of the cecum. The patient underwent a right ileo-colectomy and ileocolostomy. Histologic analysis of the operatory specimen confirmed the diagnosis of a primary Signet-ring cell carcinoma of the cecum. The recovery was uneventful, and the patient is in good health after six -months of follow-up. After completing the chemotherapy, the patient is scheduled for a colonoscopy and reversal of colostomy.

CLINICAL DISCUSSION

Colorectal primary signet ring cell carcinoma (SRCC) is a rare entity, and it is associated with poor prognosis compared with common colorectal adenocarcinomas. characterized by distinct clinical presentation, with very poor response rates.

CONCLUSION

Primary SRCC is an aggressive histological type of colon cancer and it is associated with a poor prognosis. There are no conclusive guidelines for the treatment of this type of tumor.

摘要

引言与重要性

原发性黏液腺癌是一种罕见的结直肠癌组织学亚型。其特点是临床表现独特。

病例介绍

本病例报告描述了一例罕见的盲肠原发性印戒细胞癌。一名37岁男性因肠梗阻和全身状况改变前来急诊科就诊。腹部CT扫描显示盲肠增厚上游的肠道梗阻。剖腹探查发现肠管扩张,盲肠有可疑增厚。患者接受了右半结肠切除术和回结肠造口术。手术标本的组织学分析证实为盲肠原发性印戒细胞癌。恢复过程顺利,随访6个月后患者健康状况良好。完成化疗后,患者计划接受结肠镜检查和结肠造口还纳术。

临床讨论

结直肠原发性印戒细胞癌(SRCC)是一种罕见的疾病,与常见的结直肠腺癌相比,其预后较差。临床表现独特,反应率极低。

结论

原发性SRCC是一种侵袭性的结肠癌组织学类型,预后较差。对于这类肿瘤的治疗尚无确凿的指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ae/9400076/f2f6eb8ef995/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ae/9400076/bc07fd60ce84/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ae/9400076/ab8baeb16c11/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ae/9400076/f2f6eb8ef995/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ae/9400076/bc07fd60ce84/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ae/9400076/ab8baeb16c11/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ae/9400076/f2f6eb8ef995/gr3.jpg

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