Jha Vikas Chandra, Alam Shahnawaz, Jha Neeraj
Department of Neurosurgery, All India Institute of Medical Sciences, Patna, Bihar, India.
Asian J Neurosurg. 2023 Mar 31;18(1):196-200. doi: 10.1055/s-0043-1768249. eCollection 2023 Mar.
Presentation of cervico-thoracic extradural hematoma in pediatric age is rare with stroke-like features. Its association with COVID-19 in the active stage of the disease had not been reported and its management presents a management dilemma as COVID-19 with stroke-like features. A 14-year-old boy was referred to our institute with complaints of sudden-onset upper and middle back pain, associated with loss of sensation below the middle of the back, sudden progressive weakness of both lower limbs (power 0/5) and upper limbs (power grade-2/5), and incontinence of urine, following bouts of vomiting 12 days back. There was no history of trauma, bleeding diathesis, etc. Blood investigation was suggestive of leukocytosis, and RT-PCR test for COVID-19 was positive with raised D-dimer, serum ferritin, and C-reactive protein. MRI spine was suggestive of cervicothoracic extradural hematoma extending from C5-D3 level and compressing the spinal cord. The patient refused surgical decompression and was managed conservatively, following which he improved with power grade in limbs to 4/5. Surgical decompression is the treatment of choice but the patient can sometimes improve on medical management. Association of COVID-19 with spontaneous cervicothoracic extradural hematoma had not been reported earlier in the active stage, but its role in inducing vasculopathy and increased chances of bleeding at the uncommon site had been reported in the literature, and it may precipitate such cervical epidural hematoma.
小儿颈胸段硬膜外血肿伴类似中风症状的表现罕见。其在疾病活跃期与 COVID-19 的关联此前未见报道,且其治疗面临两难境地,因为 COVID-19 伴有类似中风的症状。一名 14 岁男孩因 12 天前出现呕吐,随后突发中上背部疼痛,并伴有背部中部以下感觉丧失、双下肢(肌力 0/5)和上肢(肌力 2/5 级)突然进行性无力以及尿失禁,被转诊至我院。无外伤、出血性疾病等病史。血液检查提示白细胞增多,COVID-19 的 RT-PCR 检测呈阳性,D-二聚体、血清铁蛋白和 C 反应蛋白升高。脊柱 MRI 提示颈胸段硬膜外血肿,从 C5 至 D3 水平延伸并压迫脊髓。患者拒绝手术减压,接受保守治疗,之后肢体肌力改善至 4/5。手术减压是首选治疗方法,但患者有时通过药物治疗也可改善。COVID-19 与自发性颈胸段硬膜外血肿在疾病活跃期的关联此前未见报道,但文献报道其在诱发血管病变以及增加罕见部位出血几率方面的作用,且可能促使此类颈椎硬膜外血肿的发生。