Saghebdoust Sajjad, Habibi Mohammad Amin, Ekrami Mehran, Khadivar Farshid, Vakilzadeh Mohammad Moein, Zare Reza
Department of Neurosurgery, Razavi Hospital, Mashhad, Iran.
Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran.
Asian J Neurosurg. 2023 Apr 3;18(1):191-195. doi: 10.1055/s-0043-1763525. eCollection 2023 Mar.
Intracranial schwannomas (ISs) account for approximately 8% of intracranial tumors, while IS, a rare entity, is responsible for roughly 1% of IS. A 33-year-old man with a 3-month headache and sudden onset seizure was referred to our clinic. Preoperative magnetic resonance imaging revealed a contrast-enhancing mass accompanied by cystic components in the right temporal lobe. Ganglioglioma, metastasis, or glioblastoma multiforme was suspected, and surgery was advised. During surgery, gross total resection of a noninvasive tumor was conducted. Postoperative recovery was uneventful. Based on histopathological examination and confirmatory immunohistochemistry, the intraparenchymal temporal tumor was diagnosed as schwannoma. ISs are extremely scarce brain tumors mainly located on the surface of the brain or adjacent brain ventricles. The definite preoperative diagnosis of schwannoma cannot be readily established due to radiologically indistinguishable features from metastasis and gliomas; however, histopathology and immunohistochemistry are of great assistance. Complete surgical removal is the most preferred treatment alternative with a long-term favorable prognosis without adjuvant and neoadjuvant chemotherapy requirements.
颅内神经鞘瘤（ISs）约占颅内肿瘤的8%，而孤立性神经鞘瘤（IS）是一种罕见的实体，约占ISs的1%。一名33岁男性，有3个月的头痛史且突然发作癫痫，被转诊至我院。术前磁共振成像显示右侧颞叶有一个强化肿块并伴有囊性成分。怀疑为神经节胶质瘤、转移瘤或多形性胶质母细胞瘤，建议手术治疗。手术中，对一个非侵袭性肿瘤进行了全切除。术后恢复顺利。根据组织病理学检查和免疫组化确诊，脑实质内颞叶肿瘤被诊断为神经鞘瘤。ISs是极其罕见的脑肿瘤，主要位于脑表面或邻近脑室。由于在放射学上与转移瘤和胶质瘤特征难以区分，神经鞘瘤术前难以明确诊断；然而，组织病理学和免疫组化有很大帮助。完整的手术切除是最优选的治疗方法，长期预后良好，无需辅助和新辅助化疗。
