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[采用聚乙二醇沉淀法检测正常妊娠及妊娠高血压综合征孕妇血清中的循环免疫复合物]

[Detection of circulating immune complexes in the serum of pregnant patients in normal pregnancy and in pregnancy-induced hypertension using precipitation by polyethylene glycol].

作者信息

Reincke I, Straube W, Briese V

出版信息

Zentralbl Gynakol. 1986;108(4):238-45.

PMID:3705791
Abstract

30 non-pregnant women, 250 women with normal pregnancy and 130 women with pregnancy induced hypertension (PIH) have been examined to show the presence of circulating immune complexes in serum. The immune complex concentration in normal pregnancy shows a rapid decrease from 6th up to 12th gestational week, then a plateau near to 35th week and further a slight increase. Decrease and increase can be described only with hypothesis. The immune complex concentration in 1st and 3rd trimenon of normal pregnancy was significantly different to non-pregnant women. As like as the group of normal pregnancies the women with PIH showed an increase of immune complex concentration on a higher level, but the differences between both groups were not significant.

摘要

对30名未孕女性、250名正常妊娠女性和130名妊娠高血压综合征(PIH)女性进行了检查,以检测血清中循环免疫复合物的存在情况。正常妊娠时免疫复合物浓度在妊娠第6周至第12周迅速下降,然后在接近第35周时趋于平稳,之后略有上升。下降和上升情况只能用假设来描述。正常妊娠第一和第三孕期的免疫复合物浓度与未孕女性有显著差异。与正常妊娠组一样,PIH女性的免疫复合物浓度在更高水平上有所增加,但两组之间的差异不显著。

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