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[放射性核素显像巨噬细胞网状内皮系统在多发性硬化中的诊断价值]

[Diagnostic value of radionuclide visualization of the reticuloendothelial system of macrophages in multiple sclerosis].

作者信息

El'chaninov A P, Artiushkin A V, Skoromets A A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(2):200-3.

PMID:3705822
Abstract

Scintigraphic examination of the liver, spleen, bone marrow and retroperitoneal lymph nodes with the help of colloidal radiopharmaceutical 113mIn was conducted in 55 patients with multiple sclerosis (MS) and in 13 patients with other diseases of the nervous system. The authors ascertained dysfunction of cells of the mononuclear phagocytic system (MPS) in the MS patients. Clinical manifestations of the disease were found to correlate with the findings of radionuclide imaging of the parenchymatous organs and lymph nodes. A conclusion was drawn about the total disruption of the functional activity of MPS cells in MS and the inevitable involvement of the liver in the pathogenesis of the disease.

摘要

借助胶体放射性药物113mIn对55例多发性硬化症(MS)患者和13例患有其他神经系统疾病的患者进行了肝脏、脾脏、骨髓和腹膜后淋巴结的闪烁扫描检查。作者确定了MS患者单核吞噬细胞系统(MPS)细胞功能障碍。发现该疾病的临床表现与实质性器官和淋巴结的放射性核素成像结果相关。得出结论,MS中MPS细胞的功能活动完全中断,且肝脏不可避免地参与了该疾病的发病机制。

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Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(2):200-3.
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