Faculty of Medicine and Health, Reproduction and Perinatal Centre, Women and Babies Research, The University of Sydney, Sydney, New South Wales, Australia.
NSW Biostatistics Training Program, NSW Ministry of Health, Sydney, New South Wales, Australia.
Aust N Z J Obstet Gynaecol. 2023 Aug;63(4):541-549. doi: 10.1111/ajo.13685. Epub 2023 Apr 16.
Little research has focused on understanding trends in early gestation (20-27 weeks) stillbirths and neonatal deaths.
To examine trends in early gestation stillbirths and neonatal deaths in New South Wales (NSW), Australia.
Population-based cohort study of all births ≥20 weeks gestation among female NSW residents during 2002 to 2019, induced pregnancy terminations excluded. Stillbirth rates by gestational age and birth year were calculated per 1000 fetuses-at-risk (FAR). Neonatal death rates by gestational age and birth year were calculated per 1000 live births. Linear regression was used to examine trends in stillbirth and neonatal death rates among all, singleton and twin births.
Declining trends in early gestation stillbirth and neonatal death rates were found. Stillbirth rates decreased from 1.9 and 0.9/1000 FAR in 2002 to 1.6 and 0.7 in 2019 for 20-23 and 24-27 week groups, respectively. Neonatal rates decreased from 940 and 315/1000 live births in 2002 to 925 and 189 in 2019 for the 20-23 and 24-27 week groups, respectively. Among singleton births, declining trends in stillbirth and neonatal death rates across all age groups were observed, except for 37-38 week stillbirths. No trends in twin stillbirth rates were found across gestational age groups, although a decreasing trend was observed for 20-23 week twin neonatal deaths.
Trends in early gestation stillbirth and neonatal deaths have declined in recent decades in NSW but further efforts are needed to reduce both early and late gestation stillbirth rates among twin births.
很少有研究关注 20-27 孕周(早期妊娠)的死产和新生儿死亡趋势。
在澳大利亚新南威尔士州(NSW),检查 2002 年至 2019 年期间所有 20 周以上妊娠的女性居民的早期妊娠死产和新生儿死亡趋势。
这是一项基于人群的队列研究,排除诱导性妊娠终止,研究对象为所有 2002 年至 2019 年期间妊娠≥20 周的 NSW 女性居民。按每 1000 个胎儿风险(FAR)计算每个胎龄和出生年份的死产率。按每 1000 例活产计算每个胎龄和出生年份的新生儿死亡率。线性回归用于检查所有、单胎和双胎出生的死产率和新生儿死亡率的趋势。
发现早期妊娠死产率和新生儿死亡率呈下降趋势。20-23 周和 24-27 周组的死产率分别从 2002 年的 1.9 和 0.9/1000 FAR 降至 2019 年的 1.6 和 0.7;20-23 周和 24-27 周组的新生儿死亡率分别从 2002 年的 940 和 315/1000 活产降至 2019 年的 925 和 189。在单胎出生中,除了 37-38 周的死产外,所有年龄组的死产和新生儿死亡率均呈下降趋势。在所有胎龄组中,双胎死产率没有趋势,但 20-23 周的双胎新生儿死亡率呈下降趋势。
在最近几十年,新南威尔士州的早期妊娠死产和新生儿死亡趋势有所下降,但仍需要进一步努力降低双胎妊娠的早期和晚期妊娠死产率。