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一例罕见病例:尽管进行了双重创伤手术,但并发青少年类风湿关节炎导致脓毒症参数严重升高。

A rare case of severely elevated septic parameters caused by intercurrent juvenile rheumatoid arthritis despite dual trauma surgery.

作者信息

Wurm Lennard M, Andresen Julian R, Reinke Justyna, Poddubnyy Denis, Ertel Wolfgang, Jagielski Michal W

机构信息

Department of Traumatology and Reconstructive Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

Medical Faculty Heinrich-Heine University and University Hospital Düsseldorf, Düsseldorf, Germany.

出版信息

J Surg Case Rep. 2023 Apr 12;2023(4):rjad168. doi: 10.1093/jscr/rjad168. eCollection 2023 Apr.

Abstract

Procalcitonin (PCT) and C-reactive protein (CRP) are considered markers used in clinical practice to differentiate bacterial infections from autoimmune origin. Here we evaluate a rare case of a male patient diagnosed with juvenile idiopathic arthritis. The patient presented repeatedly to our department with atraumatic femoral head necrosis, traumatic medial femoral neck fracture and peri-implant femoral fracture. While undergoing repeated surgical interventions including a removal of osteosynthesis material and total endoprosthesis of his right hip including double subtrochanteric osteotomy, the patient developed drastically increasing infection parameters of PCT and CRP. After a completely inconspicuous revision we revealed the untypical genesis of a rheumatic cause. Consequently, we emphasize this etiology to be considered in further decision making for trauma surgery.

摘要

降钙素原(PCT)和C反应蛋白(CRP)被认为是临床实践中用于区分细菌感染和自身免疫性病因的标志物。在此,我们评估了一例罕见的男性青少年特发性关节炎患者。该患者因非创伤性股骨头坏死、创伤性股骨内侧颈骨折和植入物周围股骨骨折反复前来我院就诊。在接受包括取出内固定材料和右侧髋关节全关节置换术(包括双侧转子下截骨术)在内的多次手术干预期间,患者降钙素原(PCT)和C反应蛋白(CRP)的感染参数急剧上升。在一次完全无异常的翻修手术后,我们发现了风湿性病因的非典型起源。因此,我们强调在创伤外科的进一步决策中应考虑这种病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b198/10097544/2575f4a0a3f4/rjad168f1.jpg

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