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水痘带状疱疹病毒血管炎所致皮疹、面部下垂及多灶性颅内狭窄

Rash, Facial Droop, and Multifocal Intracranial Stenosis Due to Varicella Zoster Virus Vasculitis.

作者信息

Bilodeau Philippe-Antoine, Aghajan Yasmin, Izzy Saef

机构信息

Brigham and Women's Hospital, Boston, MA, USA.

出版信息

Neurohospitalist. 2023 Apr;13(2):178-182. doi: 10.1177/19418744221150301. Epub 2023 Mar 21.

Abstract

: This is a case of multifocal intracranial stenosis in a 74 year old male ultimately discovered to be due to Varicella Zoster Virus infection. : We highlight the importance of a broad differential diagnosis, even when the most likely etiology of intracranial stenosis is atherosclerosis. Our paper reviews the differential diagnosis as well as "red flags" for intracranial vasculopathy. Even though intracranial atherosclerotic disease is the most common cause of vasculopathy, infectious or inflammatory vasculitis should be considered on the differential. : Before considering bypass surgery or other invasive neurosurgical procedures, ensure reversible causes of vasculopathy have been ruled out. The presence of cranial neuropathies, rash, and/or elevated inflammatory markers should be red flags for vasculitis in patients presenting with stroke.

摘要

这是一例74岁男性的多灶性颅内狭窄病例,最终发现是由水痘带状疱疹病毒感染所致。我们强调了广泛鉴别诊断的重要性,即便颅内狭窄最可能的病因是动脉粥样硬化。我们的论文回顾了颅内血管病变的鉴别诊断以及“警示信号”。尽管颅内动脉粥样硬化疾病是血管病变最常见的病因,但在鉴别诊断时应考虑感染性或炎性血管炎。在考虑搭桥手术或其他侵入性神经外科手术之前,要确保已排除血管病变的可逆性病因。对于出现中风的患者,颅神经病变、皮疹和/或炎症标志物升高应是血管炎的警示信号。

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