Alkhateb Ouwais, Daaboul Obada, Daaboul Bisher, Abouharb Raed, Alazmeh Mhd Anas, Hamed Ghiath
School of Medicine, Damascus University, Damascus, Syrian Arab Republic.
Gastroenterology and Hepatology, Medical Care Center, Damascus, Syrian Arab Republic.
Case Rep Gastroenterol. 2023 Apr 11;17(1):185-190. doi: 10.1159/000529044. eCollection 2023 Jan-Dec.
Glomus tumor (glomus cell tumor) is a rare, often benign neoplasm, which is, in most cases, seen as a solitary bluish nodule involving the nail beds. Solid glomus tumor, glomangioma, and glomangiomyoma are the three main histopathological variants. In this case report, we present the rarest subtype of a glomus tumor, glomangiomyoma, in an atypical location: the stomach. A 45-year-old female from Syria presented to the clinic with severe dizziness and left epigastric abdominal pain accompanied by melena. We performed a thorough clinical study, laboratory workup, upper gastrointestinal endoscopy, endoscopic ultrasound, CT scan, as well as macroscopic and microscopic histologic examination of the surgical specimen, in addition to the immunohistochemical staining. Although rare, gastric glomangiomyoma was diagnosed and a 4.5 × 3 × 3 cm soft tissue mass was resected from the gastric antrum, and no clinical or endoscopic evidence of recurrence was observed for the follow-up duration of 4 years. Undiagnosed gastric lesions with unexplained symptoms should be further investigated and not be disregarded immediately. To the best of our knowledge, this is only the second report of an instance of gastric glomangiomyoma.
血管球瘤（血管球细胞瘤）是一种罕见的、通常为良性的肿瘤，在大多数情况下，表现为累及甲床的单个蓝色小结节。实体性血管球瘤、血管球血管瘤和血管球血管肌瘤是三种主要的组织病理学变体。在本病例报告中，我们呈现了血管球瘤最罕见的亚型——血管球血管肌瘤，其位于非典型部位：胃。一名来自叙利亚的45岁女性因严重头晕、左上腹腹痛伴黑便就诊于诊所。我们进行了全面的临床研究、实验室检查、上消化道内镜检查、内镜超声检查、CT扫描，以及对手术标本进行大体和显微镜组织学检查，此外还进行了免疫组织化学染色。尽管罕见，但诊断为胃血管球血管肌瘤，并从胃窦切除了一个4.5×3×3cm的软组织肿块，在4年的随访期内未观察到复发的临床或内镜证据。对于有无法解释症状的未确诊胃部病变应进一步检查，不应立即忽视。据我们所知，这仅是胃血管球血管肌瘤病例的第二篇报道。
