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一例由潜在转移性黑色素瘤引起的空肠-空肠套叠病例。

A Case of Jejuno-Jejunal Intussusception Caused by Underlying Metastatic Melanoma.

作者信息

Ahdi Hardeep S, Kruchko David, Asado Nahren, Kakodkar Samir

机构信息

Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA.

Gastroenterology and Hepatology, Advocate Lutheran General Hospital, Park Ridge, USA.

出版信息

Cureus. 2023 Mar 16;15(3):e36217. doi: 10.7759/cureus.36217. eCollection 2023 Mar.

DOI:10.7759/cureus.36217
PMID:37065309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10103802/
Abstract

Intussusception in adults is a rare finding with a majority of cases occurring in the pediatric population. It occurs infrequently and its presentation, etiology, and treatment differ from childhood intussusception. When discovered in adults, it raises suspicion for a neoplastic process serving as the pathological lead point. Cross-sectional imaging is the primary study of choice for diagnosis, but at times, a more invasive approach involving an exploratory laparotomy is required posing an increased risk for morbidity and mortality. Here we present a 64-year-old male who was found to have jejunal-jejunal intussusception that was surgically removed with pathology revealing metastatic melanoma as the lead point. This case highlights a unique presentation of a melanoma that was previously eradicated with immunotherapy and now had metastasized to the intestine many years later.

摘要

成人肠套叠是一种罕见的病症,大多数病例发生在儿科人群中。它很少见,其表现、病因和治疗方法与儿童肠套叠不同。在成人中发现时,会引发对作为病理引导点的肿瘤性病变的怀疑。横断面成像检查是诊断的主要选择,但有时需要采用更具侵入性的剖腹探查术,这会增加发病和死亡风险。在此,我们报告一名64岁男性,他被发现患有空肠-空肠套叠,通过手术切除,病理显示转移性黑色素瘤为引导点。该病例突出了黑色素瘤的一种独特表现,该黑色素瘤此前已通过免疫疗法根除,多年后转移至肠道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/8e34057f6160/cureus-0015-00000036217-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/544609fc176a/cureus-0015-00000036217-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/3a4df77b46aa/cureus-0015-00000036217-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/cec0be281b91/cureus-0015-00000036217-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/f746970f4df6/cureus-0015-00000036217-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/8e34057f6160/cureus-0015-00000036217-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/544609fc176a/cureus-0015-00000036217-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/3a4df77b46aa/cureus-0015-00000036217-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/cec0be281b91/cureus-0015-00000036217-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/f746970f4df6/cureus-0015-00000036217-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3905/10103802/8e34057f6160/cureus-0015-00000036217-i05.jpg

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本文引用的文献

1
Bowel Intussusception in Adults: Think Cancer!成人肠套叠:警惕癌症!
Case Rep Gastroenterol. 2020 Jan 20;14(1):27-33. doi: 10.1159/000505511. eCollection 2020 Jan-Apr.
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Intussusception in the Geriatric Population: A Case Report.老年人群中的肠套叠:一例报告
Cureus. 2022 May 2;14(5):e24663. doi: 10.7759/cureus.24663. eCollection 2022 May.
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Metastatic melanoma to the small bowel causing intussusception: A case report.小肠转移性黑色素瘤致肠套叠:一例报告
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Small Bowel Intussusception Caused by Metastatic Melanoma: A Case Report.转移性黑色素瘤导致的小肠套叠:一例报告
Cureus. 2019 Jul 27;11(7):e5251. doi: 10.7759/cureus.5251.
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Adult intussusception: a systematic review and meta-analysis.成人肠套叠:系统评价和荟萃分析。
Tech Coloproctol. 2019 Apr;23(4):315-324. doi: 10.1007/s10151-019-01980-5. Epub 2019 Apr 22.
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An unusual presentation of metastatic malignant melanoma causing jejuno-jejunal intussusception: a case report.转移性恶性黑色素瘤导致空肠-空肠套叠的罕见表现:一例报告
J Med Case Rep. 2018 Nov 13;12(1):337. doi: 10.1186/s13256-018-1887-5.
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Distant melanoma causing small bowel obstruction.远处黑色素瘤导致小肠梗阻。
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Int J Surg Case Rep. 2016;20:142-6. doi: 10.1016/j.ijscr.2016.01.019. Epub 2016 Jan 22.
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Long-term follow-up for melanoma patients: is there any evidence of a benefit?黑色素瘤患者的长期随访:是否有获益的证据?
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Adult intussusception.成人肠套叠
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