Zhang Nan, Yang Linfeng, Han Aiqing, Wang Yuanyuan, Zhao Guiwu, Wang Yue, Chen Tao
Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Department of Radiology, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Front Neurosci. 2023 Mar 31;17:1144867. doi: 10.3389/fnins.2023.1144867. eCollection 2023.
Preeclampsia (PE)-related reversible posterior leukoencephalopathy syndrome (RPLS) is a common complication of hypertensive disorders of pregnancy. The syndrome usually occurs after 20 weeks of gestation and can lead to brain injury. Severe headache, seizures, disturbance of consciousness, and other neurological symptoms may occur in severe cases. PE-RPLS has high morbidity and mortality rates and seriously damages maternal and fetal health. In recent years, the continuous advancement of medical imaging technology has provided an important imaging basis for the early diagnosis and prognostic evaluation of RPLS. This article mainly details the research status of the etiology and pathogenesis of PE-RPLS and describes its characteristic imaging findings, especially MRI findings, to provide new insights into its early diagnosis, early treatment, and improvement of prognosis.
子痫前期（PE）相关的可逆性后部白质脑病综合征（RPLS）是妊娠期高血压疾病的常见并发症。该综合征通常发生在妊娠20周后，可导致脑损伤。严重病例可能出现严重头痛、癫痫发作、意识障碍及其他神经症状。PE-RPLS发病率和死亡率高，严重损害母婴健康。近年来，医学影像技术的不断进步为RPLS的早期诊断和预后评估提供了重要的影像学依据。本文主要详述PE-RPLS的病因及发病机制的研究现状，并描述其特征性影像学表现，尤其是MRI表现，为其早期诊断、早期治疗及改善预后提供新的见解。
