通过抗菌药物管理团队干预和基于治疗药物监测的阿米卡星治疗成功治愈一例产金属β-内酰胺酶菌血症病例
Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment.
作者信息
Koishi Noriko, Sasano Hiroshi, Yoshizawa Toshihiro, Shikuri Mika, Matsumoto Hiroshi, Suzuki Mai, Fukui Yukiko, Chonan Masayoshi, Kimura Toshimi, Ichida Hirofumi, Saiura Akio, Naito Toshio
机构信息
Department of Pharmacy, Juntendo University Hospital, Tokyo, Japan.
Department of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.
出版信息
Case Rep Infect Dis. 2023 Apr 7;2023:5574769. doi: 10.1155/2023/5574769. eCollection 2023.
An 80-year-old woman underwent pancreatoduodenectomy. Post-operation, she experienced a fever, and a culture of blood revealed metallo-beta-lactamase-producing For treatments with aminoglycoside antimicrobial agents, a therapeutic drug monitoring-based dosing design can lower the risk of adverse events and enable appropriate treatment. . When aminoglycoside antimicrobial agents are administered for MBL-producing bacteremia, prescription suggestions based on TDM by antimicrobial stewardship team can reduce the occurrence of adverse events and enable appropriate treatment.
一名80岁女性接受了胰十二指肠切除术。术后，她出现发热，血液培养显示产金属β-内酰胺酶。对于氨基糖苷类抗菌药物治疗，基于治疗药物监测的给药方案设计可降低不良事件风险并实现恰当治疗。当使用氨基糖苷类抗菌药物治疗产MBL菌血症时，抗菌管理团队基于TDM的处方建议可减少不良事件的发生并实现恰当治疗。
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