Department of Cardiology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Food Environ Virol. 2023 Jun;15(2):107-115. doi: 10.1007/s12560-022-09545-w. Epub 2023 Apr 17.
This study aimed to investigate the effect of different environmental disinfection methods on reducing contaminated surfaces (CSs) by the Omicron BA.2.2 variant of SARS-CoV-2 in the fever clinic between March 20 and May 30, 2022, and to analyze the influences and related factors of CSs. This study includes survey data from 389 positive patients (SPPs) and 204 CSs in the fever clinic, including the CS type, disinfection method, length of time spent in the clinic, cycle threshold (CT) value, name, age, weight, mask type, mask-wearing compliance, hand-mouth touch frequency and sex. Associations between study variables and specified outcomes were explored using univariate regression analyses. Mask-wearing compliance had a significant negative correlation with CSs (r = - 0.446, P = 0.037). Among the 389 SPPs, 22 SPPs (CRP, 5.66%) caused CSs in the separate isolation room. A total of 219 SPPs (56.30%) were male. The mean age of SPPs was 4.34 ± 3.92 years old, and the mean CT value was 12.44 ± 5.11. In total, 9952 samples with exposure history were taken, including 204 (2.05%) CSs. Among the CSs, the positive rate of flat surfaces was the highest in public areas (2.52%) and separate isolation rooms (4.75%). Disinfection methods of ultraviolet radiation + chemical irradiation significantly reduced the CSs in both the public area (0% vs. 4.56%) and the separate isolation room (0.76% vs. 2.64%) compared with the chemical method alone (P < 0.05). Compared with ordinary SPPs, CRPs were older (6.04 year vs. 4.23 year), and the male proportion was higher (72.73% vs. 55.31%). In particular, it was found that SPPs contaminated their surroundings and therefore imposed risks on other people. Environmental disinfection with ultraviolet radiation + chemical treatment should be emphasized. The findings may be useful to guide infection control practices for the Omicron BA.2.2 variant of SARS-CoV-2.
本研究旨在探讨不同环境消毒方法对 2022 年 3 月 20 日至 5 月 30 日发热门诊中 SARS-CoV-2 奥密克戎 BA.2.2 变异株污染表面（CSs）的减少效果，并分析 CSs 的影响因素和相关因素。本研究包括发热门诊 389 例阳性患者（SPP）和 204 例 CS 的调查数据，包括 CS 类型、消毒方法、在诊时间、循环阈值（CT）值、姓名、年龄、体重、口罩类型、口罩佩戴依从性、手口接触频率和性别。使用单变量回归分析探讨研究变量与指定结果之间的关联。口罩佩戴依从性与 CSs 呈显著负相关（r = -0.446，P = 0.037）。在 389 例 SPP 中，22 例 SPP（CRP，5.66%）导致单独隔离室的 CSs。共有 219 例 SPP（56.30%）为男性。SPP 的平均年龄为 4.34 ± 3.92 岁，平均 CT 值为 12.44 ± 5.11。共采集有暴露史的样本 9952 例，其中 CSs 204 例。在 CSs 中，公共区域（2.52%）和单独隔离室（4.75%）的平面表面阳性率最高。紫外线辐射+化学照射消毒方法与单独使用化学方法相比，明显降低了公共区域（0%比 4.56%）和单独隔离室（0.76%比 2.64%）的 CSs（P<0.05）。与普通 SPP 相比，CRPs 年龄更大（6.04 岁 vs. 4.23 岁），男性比例更高（72.73% vs. 55.31%）。特别是，发现 SPP 污染了周围环境，因此对其他人构成了风险。应强调紫外线辐射+化学处理的环境消毒。这些发现可能有助于指导 SARS-CoV-2 奥密克戎 BA.2.2 变异株的感染控制实践。
