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青少年患者骨盆尤文肉瘤根治性切除术后通过股骨近端上移和全髋关节置换进行骨盆重建:1例报告及文献复习

Pelvis reconstruction by proximal femur upshifting and total hip arthroplasty after radical resection of an adolescent patient pelvic Ewing's sarcoma, a case report, and literature review.

作者信息

Mahran Mohamed A, Khalifa Ahmed A, El-Sayed Amr

机构信息

Orthopaedic Department, Assiut University Hospital, Assiut, Egypt.

Orthopaedic Department, Qena Faculty of Medicine and University Hospital, South Valley University, Qena, Egypt.

出版信息

Int J Surg Case Rep. 2023 May;106:108146. doi: 10.1016/j.ijscr.2023.108146. Epub 2023 Apr 12.

Abstract

INTRODUCTION AND IMPORTANCE

Pelvis reconstruction after tumor resection poses a challenge, especially in younger patients where preserving the patient's function and mobility is paramount.

CASE PRESENTATION

A 16 years old female presented in March 2019 with vague right iliac area pain, diagnosed as pelvic Ewing's sarcoma after imaging studies (MRI and MSCT scan) and obtaining an incisional biopsy. After initial chemotherapy cycles, the tumor decreased in size, and surgical intervention in two stages was performed. The first stage was in October 2019 and consisted of pelvic resection type I and II according to Enneking and Dunham classification, proximal femur upshifting to compensate for the pelvic bone defect, and a cement spacer to fill the space of the resected proximal femur. The second stage was performed after two months and consisted of implanting a total hip arthroplasty using Megaprostheses and a cementless dual mobility acetabular cup. No local recurrence or distant metastases were detected during follow-ups. At the final follow up after 36 months, the patient showed acceptable functional outcomes (HHS score 83, and MSTS score 23 (76.7 %) points), and the radiographs showed proper implant positioning and stability.

CLINICAL DISCUSSION

Treating pelvic Ewing's sarcoma requires a multidisciplinary team. After surgical resection, the pelvic reconstruction options include using allografts or autografts, femur upshifting, and hemipelvis prostheses, which should be chosen considering patients and tumor characteristics as well as surgical team efficiency.

CONCLUSION

Reconstructing the pelvic defect after bone tumor resection by proximal femoral upshifting is a valid biological option with acceptable outcomes.

摘要

引言与重要性

肿瘤切除术后的骨盆重建是一项挑战,尤其对于年轻患者而言,保留其功能和活动能力至关重要。

病例介绍

一名16岁女性于2019年3月因右髂部隐痛就诊,经影像学检查(MRI和MSCT扫描)及切开活检后被诊断为骨盆尤因肉瘤。经过初始化疗周期后,肿瘤体积缩小,遂分两阶段进行手术干预。第一阶段于2019年10月进行,包括根据Enneking和Dunham分类进行I型和II型骨盆切除术、股骨近端上移以补偿骨盆骨缺损,以及使用骨水泥间隔物填充切除的股骨近端空间。第二阶段在两个月后进行,包括使用Megaprostheses全髋关节置换术和非骨水泥双动髋臼杯植入。随访期间未发现局部复发或远处转移。在36个月后的最后随访中,患者显示出可接受的功能结果(HHS评分83分,MSTS评分23分(76.7%)),X线片显示植入物位置正确且稳定。

临床讨论

治疗骨盆尤因肉瘤需要多学科团队。手术切除后,骨盆重建选择包括使用同种异体骨或自体骨、股骨上移和半骨盆假体,应根据患者和肿瘤特征以及手术团队的效率来选择。

结论

通过股骨近端上移重建骨肿瘤切除后的骨盆缺损是一种有效的生物学选择,结果可接受。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/680d/10130465/825c9edcc0b1/gr1.jpg

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