"Paradoxical neoantigenic mutations": not simply a driver vs passenger dualism.
作者信息
Meng Xiang-Yu
机构信息
College of Basic Medical Sciences, Medical School, Hubei Minzu University, 39 Xueyuan Road, Enshi, 445000, China.
出版信息
Br J Cancer. 2023 Jul;129(1):1-2. doi: 10.1038/s41416-023-02270-6. Epub 2023 Apr 17.
Abstract
摘要
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本文引用的文献
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Somatic mutations can induce a noninflamed tumour microenvironment via their original gene functions, despite deriving neoantigens.体细胞突变可以通过其原始基因功能诱导非炎症性肿瘤微环境，尽管会产生新抗原。
Br J Cancer. 2023 Apr;128(6):1166-1175. doi: 10.1038/s41416-023-02165-6. Epub 2023 Feb 2.
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TSNAdb v2.0: The Updated Version of Tumor-specific Neoantigen Database.TSNAdb v2.0：肿瘤特异性新抗原数据库的更新版本。
Genomics Proteomics Bioinformatics. 2023 Apr;21(2):259-266. doi: 10.1016/j.gpb.2022.09.012. Epub 2022 Oct 6.
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eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants.基于表达的变异影响表型分析预测基因变异的功能。
PLoS Comput Biol. 2021 Jul 2;17(7):e1009132. doi: 10.1371/journal.pcbi.1009132. eCollection 2021 Jul.
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Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.肿瘤和 T 细胞内在机制对检查点抑制敏感性的荟萃分析。
Cell. 2021 Feb 4;184(3):596-614.e14. doi: 10.1016/j.cell.2021.01.002. Epub 2021 Jan 27.
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The repertoire of mutational signatures in human cancer.人类癌症中的突变特征谱。
Nature. 2020 Feb;578(7793):94-101. doi: 10.1038/s41586-020-1943-3. Epub 2020 Feb 5.
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APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy.载脂蛋白B编辑复合体相关诱变与新肽疏水性：对免疫治疗反应的影响
Oncoimmunology. 2018 Dec 24;8(3):1550341. doi: 10.1080/2162402X.2018.1550341. eCollection 2019.
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