Viallat J R, Farisse P, Rey F, Boutin C, Henin Y, Jausseran M, D'Istria J C
Ann Otolaryngol Chir Cervicofac. 1986;103(1):63-6.
Two hundred subjects were evaluated using a standardised questionnaire in order to determine possible exposure to asbestos: 50 patients with a carcinoma of the larynx (mean age: 59.2 +/- 1.6 years), 50 patients with a carcinoma of the bronchus (mean age 61.2 +/- 1.5 years) and 100 controls. Rates concerning exposure to asbestos were 27.8%, 23.4% and 4% respectively. The difference between the carcinoma patients and the controls was significant (p less than 0.001). The mean time lapse between the first exposure to asbestos and the development of malignant disease was shorter for the larynx (28.5 +/- 4 years) than for the lung (46.2 +/- 4.2): p less than 0.01. This study confirms the aetiological role of asbestos in the pathogenesis of carcinoma of the larynx as well as carcinoma of the lung, and raises the problem of their medicolegal compensation.
为了确定是否可能接触石棉，使用标准化问卷对200名受试者进行了评估：50名喉癌患者（平均年龄：59.2±1.6岁）、50名支气管癌患者（平均年龄61.2±1.5岁）和100名对照者。石棉接触率分别为27.8%、23.4%和4%。癌症患者与对照者之间的差异具有统计学意义（p<0.001）。首次接触石棉至恶性疾病发生的平均时间间隔，喉癌患者（28.5±4年）比肺癌患者（46.2±4.2年）短：p<0.01。本研究证实了石棉在喉癌和肺癌发病机制中的病因学作用，并提出了它们的法医学赔偿问题。
