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在洛杉矶县接受协调艾滋病毒护理的人群中,病毒抑制趋势存在种族、性别和社会心理差异。

Racial, gender, and psychosocial disparities in viral suppression trends among people receiving coordinated HIV care in Los Angeles County.

机构信息

Center for HIV Identification, Prevention and Treatment Services.

Department of Family Medicine.

出版信息

AIDS. 2023 Jul 15;37(9):1441-1449. doi: 10.1097/QAD.0000000000003578. Epub 2023 Apr 13.

DOI:10.1097/QAD.0000000000003578
PMID:37070545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10330081/
Abstract

OBJECTIVE

To longitudinally evaluate differences in HIV viral suppression (<200 copies/ml) by intersections of race/ethnicity, gender, and psychosocial issues in people with HIV in the Los Angeles County Medical Care Coordination Program.

DESIGN

We analyzed 74 649 viral load measurements over 10 184 people with HIV enrolled in the Medical Care Coordination Program between January 1, 2013 and March 1, 2020.Methods: We fit Bayesian logistic hierarchical random effects models to test interactions between gender, race/ethnicity, and a psychosocial acuity score on viral suppression over time from 1 year prior to program enrollment to 24 months after enrollment.

RESULTS

The probability of viral suppression declined prior to enrollment, then increased and stabilized by 6 months after enrollment. Black/African American patients with low and moderate psychosocial acuity scores did not achieve the same increase in percentage of viral suppression as those in other racial/ethnic groups. Transgender women with high psychosocial acuity scores took longer (about 1 year) to achieve the same percentage of viral suppression as clients of other gender identities.

CONCLUSIONS

Some racial/ethnic and gender disparities in viral suppression persisted after enrollment in the Los Angeles County Medical Care Coordination Program while accounting for psychosocial acuity score, which may be explained by factors not assessed in the program.

摘要

目的

通过洛杉矶县医疗协调计划中 HIV 感染者的种族/民族、性别和心理社会问题的交叉点,纵向评估 HIV 病毒抑制(<200 拷贝/ml)的差异。

设计

我们分析了 2013 年 1 月 1 日至 2020 年 3 月 1 日期间参加医疗协调计划的 10184 名 HIV 感染者的 74649 份病毒载量测量值。

方法

我们拟合了贝叶斯逻辑回归分层随机效应模型,以测试性别、种族/民族和心理社会敏锐度评分在从参加计划前 1 年到参加后 24 个月的时间内对病毒抑制的相互作用。

结果

在参加计划之前,病毒抑制的概率下降,然后在参加后 6 个月内增加并稳定。低和中度心理社会敏锐度评分的黑/非裔美国患者与其他种族/民族群体相比,没有增加病毒抑制的百分比。高心理社会敏锐度评分的跨性别女性需要更长的时间(约 1 年)才能达到与其他性别认同客户相同的病毒抑制百分比。

结论

在考虑到心理社会敏锐度评分后,洛杉矶县医疗协调计划中仍存在一些种族/民族和性别在病毒抑制方面的差异,这可能可以用计划中未评估的因素来解释。