Bartůňková Jiřina, Bloomfield Markéta, Havlišová Magdalena, Klocperk Adam, Kubešová Helena, Podrazil Michal, Střížová Zuzana, Šedivá Anna
Vnitr Lek. 2023 Spring;69(2):133-137. doi: 10.36290/vnl.2023.021.
The field of immunology has undergone a very significant development in recent decades, which has been reflected especially in the beginning of this millennium in significant advances in the understanding of the immune system and in the application of this knowledge in practice. The progress and acceleration of research and advances in the field of immunology was further prompt by the unexpected onset of the COVID-19 pandemic in 2020. The intense scientific work has not only led to the development of our understanding of the immune response to viruses, but also to the rapid conversion of this knowledge into practical pandemic management on a global scale, as exemplified by the development of vaccines against SARS-Cov-2 virus. The pandemic era has further contributed to the acceleration of the application of not only biological discoveries but also technological approaches into practical applications, such as use of advanced mathematics, computer science and, more recently, artificial intelligence which are all are adding to the advances that are significantly moving the field of immunology forward. In this communication, we present specific advances in particular areas of immunopathology, which are mainly allergy, immunodeficiency, immunity and infection, vaccination, autoimmune diseases and cancer immunology.
近几十年来,免疫学领域取得了非常显著的发展,这尤其体现在本世纪初对免疫系统的理解取得了重大进展,以及这一知识在实践中的应用。2020年新冠疫情的意外爆发进一步推动了免疫学领域研究的进展和加速。高强度的科研工作不仅使我们对病毒免疫反应的理解得以发展,还使这一知识迅速转化为全球范围内的实际疫情防控措施,例如针对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒的疫苗研发。疫情时代不仅推动了生物学发现的应用加速,还促进了技术方法在实际应用中的加速,如高等数学、计算机科学以及最近的人工智能的应用,所有这些都为显著推动免疫学领域前进的进展增添了助力。在本通讯中,我们介绍免疫病理学特定领域的具体进展,主要包括过敏、免疫缺陷、免疫与感染、疫苗接种、自身免疫性疾病和癌症免疫学。