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耐甲氧西林金黄色葡萄球菌性脓毒症并眶蜂窝织炎导致视网膜中央动脉和静脉阻塞:病例报告。

Methicillin-Resistant Sepsis and Orbital Cellulitis Leading to a Combined Central Retinal Artery and Vein Occlusion: A Case Report.

机构信息

Texas Tech University Health Sciences Center El Paso, USA.

出版信息

J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231165728. doi: 10.1177/23247096231165728.

DOI:10.1177/23247096231165728
PMID:37073469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10123886/
Abstract

Combined central retinal artery and vein occlusion (CCRAVO) is a rare entity characterized by features of tortuous retinal veins, retinal hemorrhage, optic disk edema and pallor, macula edema, cherry-red spot, and cotton-wool spots. The occurrence of CCRAVO in the adult population is often in the setting of systemic disease; while CCRAVO in the pediatric population is frequently associated with infection of the sinuses, preseptal cellulitis, or orbital cellulitis. It has been hypothesized that CCRAVO can result from methicillin-resistant (MRSA) sepsis-induced coagulation disturbances, orbital cellulitis, and even orbital compartment syndrome; however, there are insufficient reports of this complication. This case report sheds light on one such case with irreversible vision loss as a sequela.

摘要

视网膜中央动脉和静脉阻塞(CCRAVO)是一种罕见的疾病,其特征为视网膜静脉迂曲、视网膜出血、视盘水肿和苍白、黄斑水肿、樱桃红斑和棉絮斑。成人 CCRAVO 的发生常与系统性疾病有关;而儿科 CCRAVO 常与鼻窦感染、眶前蜂窝织炎或眶蜂窝织炎有关。据推测,CCRAVO 可能是由耐甲氧西林金黄色葡萄球菌(MRSA)败血症引起的凝血功能障碍、眶蜂窝织炎甚至眶隔综合征引起的;然而,这种并发症的报道还不够充分。本病例报告就揭示了这样一个因该并发症导致视力不可逆转丧失的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8672/10123886/f545233d2519/10.1177_23247096231165728-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8672/10123886/4151e40cbda4/10.1177_23247096231165728-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8672/10123886/e01cf06a8dab/10.1177_23247096231165728-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8672/10123886/f545233d2519/10.1177_23247096231165728-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8672/10123886/4151e40cbda4/10.1177_23247096231165728-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8672/10123886/e01cf06a8dab/10.1177_23247096231165728-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8672/10123886/f545233d2519/10.1177_23247096231165728-fig3.jpg

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本文引用的文献

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BMJ Case Rep. 2022 Mar 4;15(3):e248425. doi: 10.1136/bcr-2021-248425.
2
Heterozygous factor V Leiden mutation manifesting with combined central retinal vein occlusion, cilioretinal artery occlusion, branch retinal artery occlusion, and anterior ischaemic optic neuropathy: a case report.杂合子因子 V 莱顿突变导致的中央视网膜静脉阻塞、睫状视网膜动脉阻塞、分支视网膜动脉阻塞和前部缺血性视神经病变:一例报告。
BMC Ophthalmol. 2022 Feb 5;22(1):55. doi: 10.1186/s12886-022-02278-1.
3
Combined Central Retinal Artery and Vein Occlusion with Ischemic Optic Neuropathy After COVID-19 Vaccination.
新冠疫苗接种后合并视网膜中央动脉和静脉阻塞及缺血性视神经病变
Int Med Case Rep J. 2022 Jan 16;15:7-14. doi: 10.2147/IMCRJ.S328931. eCollection 2022.
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Unusual case of combined central retinal artery and vein occlusion in a patient with acute lymphoblastic leukemia.一名急性淋巴细胞白血病患者出现视网膜中央动脉和静脉联合阻塞的罕见病例。
J Fr Ophtalmol. 2022 Apr;45(4):e195-e197. doi: 10.1016/j.jfo.2021.08.019. Epub 2021 Dec 28.
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