Larner College of Medicine, University of Vermont, Burlington, VT, USA.
Department of Surgery, Larner College of Medicine, University of Vermont Cancer Center, University of Vermont, Burlington, VT, USA.
Int J Dermatol. 2023 Jul;62(7):850-856. doi: 10.1111/ijd.16684. Epub 2023 Apr 19.
The ongoing challenges posed by COVID-19 are concerning for their impact on successful detection and recognition of melanoma as total body skin examinations and skin biopsies are critical for identifying early-stage melanoma and intervening before progression to metastatic disease. A comprehensive electronic search of PubMed/MEDLINE was conducted on or before August 1, 2022, using the search terms ("skin" AND "COVID-19"), (["skin cancer" AND "COVID-19"] OR ["skin cancer" AND "coronavirus"]), (["melanoma" AND "COVID-19"] OR ["melanoma" AND "coronavirus"]), ("dermatology" AND "COVID-19"), and ("cutaneous" AND "COVID-19"). Eight articles representing Belgium, Chile, France, Germany, Spain, the United Kingdom, and the United States were included. Four articles analyzed changes in the proportion of in situ melanoma at diagnosis and consistently reported decreases, with an overall decrease ranging from 7.6 to 40.4%. Five studies analyzed changes in the proportion of melanoma diagnoses by staging, but no clear changes in staging patterns were observed. Five studies analyzed changes in the mean Breslow thickness of melanoma diagnoses and consistently reported increases, with an overall increase ranging from 4.0 to 38%. Disruptions to proper diagnosis and treatment of melanoma are creating undue morbidity, mortality, and healthcare costs as the pandemic continues. Continued research with improved, centralized data collection is needed to better address the COVID-19 pandemic's ongoing challenge to appropriate detection and treatment of melanoma.
COVID-19 持续带来挑战，对黑色素瘤的成功检测和识别产生影响，因为全身皮肤检查和皮肤活检对于识别早期黑色素瘤以及在疾病进展为转移性疾病之前进行干预至关重要。2022 年 8 月 1 日或之前，我们对 PubMed/MEDLINE 进行了全面的电子检索，使用的检索词为("skin" AND "COVID-19")、(["skin cancer" AND "COVID-19"] OR ["skin cancer" AND "coronavirus"]）、(["melanoma" AND "COVID-19"] OR ["melanoma" AND "coronavirus"]）、("dermatology" AND "COVID-19") 和 ("cutaneous" AND "COVID-19")。共纳入了来自比利时、智利、法国、德国、西班牙、英国和美国的 8 篇文章。其中 4 篇文章分析了诊断时原位黑色素瘤比例的变化，结果一致报告了下降，总体降幅为 7.6%至 40.4%。有 5 项研究分析了分期诊断中黑色素瘤诊断比例的变化，但没有观察到分期模式的明显变化。有 5 项研究分析了黑色素瘤诊断的平均 Breslow 厚度的变化，结果一致报告了增加，总体增加幅度为 4.0%至 38%。由于大流行的持续，黑色素瘤的正确诊断和治疗受到干扰，导致发病率、死亡率和医疗保健成本增加。需要继续进行研究，并进行改进、集中的数据收集，以更好地应对 COVID-19 大流行对黑色素瘤适当检测和治疗的持续挑战。
