补充热带水果加工副产品对Wistar大鼠血脂谱、视黄醇水平和肠道功能的影响。
Effects of supplementation of tropical fruit processing by-products on lipid profile, retinol levels and intestinal function in Wistar rats.
作者信息
Batista Kamila S, Cavalcante Hassler Clementino, Gomes Jéssyca A DE Sousa, Silva Laiane A DA, Cavalcanti Natália S DE Holanda, Garcia Estefânia F, Menezes Francisca Nayara D D, Lima Tamires A S DE, Souza Evandro L DE, Magnani Marciane, Aquino Jailane DE Souza
机构信息
Universidade Federal da Paraíba, Departamento de Nutrição, Laboratório de Nutrição Experimental -LANEX, Cidade Universitária, 58051-900 João Pessoa, PB, Brazil.
Universidade Federal da Paraíba, Departamento de Gastronomia, Centro de Tecnologia e Desenvolvimento Regional, Cidade Universitária, 58058-600 João Pessoa, PB, Brazil.
出版信息
An Acad Bras Cienc. 2023 Apr 17;95(2):e20201684. doi: 10.1590/0001-3765202320201684. eCollection 2023.
Fruits agro-industrial by-products may have a great variety of bioactive compounds that promote health. Thus, the effects of supplementation with acerola, cashew and guava processing by-products for 28 days on retinol level, lipid profile and on some aspects related to intestinal function in rats were investigated. The animals supplemented with different fruit by-products presented similar weight gain, faecal pH values and intestinal epithelial structures; however, they showed higher moisture and Lactobacillus spp. and Bifidobacterium spp. counts in faeces compared to the control group. Supplementation with the cashew by-product decreased the blood glucose, acerola and guava by-products reduced serum lipid levels and all fruit by-products tested increased serum and hepatic retinol. The results indicated that acerola and guava by-products possess a potential hypolipidemic effect. The three fruit by-products increase the hepatic retinol deposition and the faecal populations of beneficial bacterial groups and modulated aspects of intestinal function. The findings of this study can contribute to sustainable fruticulture and support future clinical studies with the supplementation of by-products.
水果农工业副产品可能含有多种促进健康的生物活性化合物。因此，研究了用针叶樱桃、腰果和番石榴加工副产品补充大鼠28天对视黄醇水平、脂质谱以及与肠道功能相关的某些方面的影响。补充不同水果副产品的动物体重增加、粪便pH值和肠道上皮结构相似；然而，与对照组相比，它们粪便中的水分、乳酸杆菌属和双歧杆菌属数量更高。补充腰果副产品可降低血糖，针叶樱桃和番石榴副产品可降低血清脂质水平，所有测试的水果副产品均可提高血清和肝脏视黄醇水平。结果表明，针叶樱桃和番石榴副产品具有潜在的降血脂作用。这三种水果副产品增加了肝脏视黄醇沉积和有益细菌群的粪便数量，并调节了肠道功能方面。本研究结果有助于可持续果树栽培，并为未来补充副产品的临床研究提供支持。
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