Department of Urology, Indiana University School of Medicine, Indianapolis, IN.
Indiana University School of Medicine, Indianapolis, IN.
Urology. 2023 Jul;177:184-188. doi: 10.1016/j.urology.2023.04.001. Epub 2023 Apr 17.
To evaluate a subset of patients who develop strictures requiring Ileal Ureter (IU) in the setting of prior urinary diversion or augmentation (ileal conduits, neobladders, continent urinary diversions). To our knowledge, there are no prior studies on patients with IU substitution into established lower urinary tract reconstructions.
A retrospective review of patients (18 years) undergoing IU creation from 1989 to 2021 was performed. A total of 160 patients were identified. In total, 19 (12%) patients had IUs into diversions. We examined demographics, stricture cause, diversion type, renal function, and postoperative complications.
Nineteen patients were identified. Sixteen were male. Mean age was 57.7(SD 17.0) years. Diversions included continent urinary reservoirs (4), neobladders (5), ileal conduits (7), and bladder augmentations with Monti channels (3). Fifteen had unilateral surgery, and 4 had bilateral "reverse 7" IU creation. Average length of stay was 7.6 days (SD 2.9). Average follow-up was 32.9 months (SD 27). Mean preoperative creatinine was 1.5 (SD 0.4); mean postoperative creatinine at most recent follow-up was 1.6 (SD 0.7). There was no significant difference between pre- and postoperative creatinine (P = .18). One patient had a ventriculoperitoneal Shunt infection resulting ventriculoperitoneal shunt externalization, 1 had Clostridium difficile infection potentially causing an entero-neobladder fistula, 2 with ileus, 1 urine leak, and 1 wound infection. None required renal replacement therapy.
Patients with urinary diversions and prior bowel reconstructive surgeries with subsequent ureteral strictures are a challenging cohort of patients. In properly selected patients, ureteral reconstruction with ileum is feasible and preserves renal function with minimal long-term complications.
评估一组在先前尿路分流或增强(回肠导管、新膀胱、 continent 尿分流)后出现需要回肠输尿管(IU)狭窄的患者。据我们所知,尚无关于 IU 替代已建立的下尿路重建的患者的先前研究。
对 1989 年至 2021 年期间进行 IU 手术的患者(18 岁)进行了回顾性分析。共确定了 160 名患者。共有 19 名(12%)患者的 IU 进入了分流。我们检查了人口统计学数据、狭窄原因、分流类型、肾功能和术后并发症。
确定了 19 名患者。16 名是男性。平均年龄为 57.7(SD 17.0)岁。分流包括 continent 尿储器(4 例)、新膀胱(5 例)、回肠导管(7 例)和 Monti 通道膀胱增强(3 例)。15 例接受了单侧手术,4 例接受了双侧“反向 7”IU 手术。平均住院时间为 7.6 天(SD 2.9)。平均随访时间为 32.9 个月(SD 27)。术前肌酐平均值为 1.5(SD 0.4);最近随访时的术后肌酐平均值为 1.6(SD 0.7)。术前和术后肌酐无显著差异(P=0.18)。1 例患者因脑室-腹腔分流感染导致脑室-腹腔分流外置,1 例患者因艰难梭菌感染可能导致肠-新膀胱瘘,2 例患者出现肠梗阻,1 例出现尿漏,1 例出现伤口感染。均无需肾脏替代治疗。
患有尿路分流和先前肠重建手术并随后出现输尿管狭窄的患者是一组具有挑战性的患者。在适当选择的患者中,回肠输尿管重建是可行的,可保留肾功能,且长期并发症较少。