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采用胸部 CT 量化肺挫伤体积预测胸部创伤患者的呼吸并发症。

Prediction of respiratory complications by quantifying lung contusion volume using chest computed tomography in patients with chest trauma.

机构信息

Department of Trauma Surgery, School of Medicine, Pusan National University, Biomedical Research Institute, Pusan National University Hospital, 179 Gudeok-Ro, Seo-Gu, Busan, 49241, Republic of Korea.

Busan Center for Medical Mathematics, National Institute for Mathematical Sciences, Daejeon, Republic of Korea.

出版信息

Sci Rep. 2023 Apr 19;13(1):6387. doi: 10.1038/s41598-023-33275-z.

Abstract

Pulmonary contusion is an important risk factor for respiratory complications in trauma patients. Hence, we aimed to determine the relationship between the ratio of pulmonary contusion volume to the total lung volume and patient outcomes and the predictability of respiratory complications. We retrospectively included 73 patients with a pulmonary contusion on chest computed tomography (CT) from 800 patients with chest trauma admitted to our facility between January 2019 and January 2020. Chest injury severity was expressed as the ratio of pulmonary contusion volume to total lung volume by quantifying pulmonary contusion volume on chest CT. The cut-off value was 80%. Among the 73 patients with pulmonary contusion (77% males, mean age: 45.3 years), 28 patients had pneumonia, and five had acute respiratory distress syndrome. The number of patients in the severe risk group with > 20% of pulmonary contusion volume was 38, among whom 23 had pneumonia. For predicting pneumonia, the area under the receiver operating characteristic curves for the ratio of pulmonary contusion volume was 0.85 (95% confidence interval 0.76-0.95, p = 0.008); the optimal threshold was 70.4%. Quantifying pulmonary contusion volume using initial CT enables identifying patients with chest trauma at high risk of delayed respiratory complications.

摘要

肺挫伤是创伤患者发生呼吸并发症的重要危险因素。因此,我们旨在确定肺挫伤体积与全肺体积的比值与患者预后的关系,以及预测呼吸并发症的可能性。我们回顾性纳入了 2019 年 1 月至 2020 年 1 月期间我院收治的 800 例胸部创伤患者中 73 例胸部 CT 显示肺挫伤的患者。胸部损伤严重程度通过胸部 CT 量化肺挫伤体积来表示为肺挫伤体积与全肺体积的比值。截断值为 80%。在 73 例肺挫伤患者(77%为男性,平均年龄:45.3 岁)中,28 例患有肺炎,5 例患有急性呼吸窘迫综合征。肺挫伤体积>20%的严重风险组患者有 38 例,其中 23 例患有肺炎。对于预测肺炎,肺挫伤体积比值的受试者工作特征曲线下面积为 0.85(95%置信区间 0.76-0.95,p=0.008);最佳阈值为 70.4%。使用初始 CT 量化肺挫伤体积可以识别胸部创伤患者中存在迟发性呼吸并发症高风险的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ffa/10115865/bfd56c33e411/41598_2023_33275_Fig1_HTML.jpg

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